Results 31 to 40 of about 53,634 (224)
Mechanochemical regulations of RPA's binding to ssDNA [PDF]
Scientific Reports, 2015 AbstractReplication protein A (RPA) is a ubiquitous eukaryotic single-stranded DNA (ssDNA) binding protein that serves to protect ssDNA from degradation and annealing and as a template for recruitment of many downstream factors in virtually all DNA transactions in cell.
Chen, Jin +4 more
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The viral etiology of tomato yellow leaf curl disease - a review
Plant Protection Science, 2009 Tomato yellow leaf curl disease (TYLCD) is one of the most devastating plant diseases in the world. As a result of its continuing rapid spread, it now afflicts more than 30 tomato growing countries in the Mediterranean basin, southern Asia, Africa, and ...
Efrat Glick, Yael Levy, Yedidya Gafni
doaj +1 more source
Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA Annealing. [PDF]
PLoS ONE, 2016 Yeast Rad52 (yRad52) has two important functions at homologous DNA recombination (HR); annealing complementary single-strand DNA (ssDNA) molecules and recruiting Rad51 recombinase onto ssDNA (recombination mediator activity).
Nilesh V Khade, Tomohiko Sugiyama
doaj +1 more source
Methods and Protocols, 2022 The high failure rate of the in vitro aptamer selection process by SELEX (Systematic Evolution of Ligands by EXponential enrichment) limits the production of these innovative oligonucleotides and, consequently, limits their potential applications.
Lisa Lucie Le Dortz +7 more
doaj +1 more source
Development of a novel, high-affinity ssDNA trypsin inhibitor
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 Inhibitors of serine proteases are not only extremely useful in the basic research but are also applied extensively in clinical settings. Using Systematic Evolution of Ligands by Exponential Enrichment (SELEX) approach we developed a family of novel ...
Stanislaw Malicki +6 more
doaj +1 more source
Single-molecule observation of ATP-independent SSB displacement by RecO in Deinococcus radiodurans
eLife, 2020 Deinococcus radiodurans (DR) survives in the presence of hundreds of double-stranded DNA (dsDNA) breaks by efficiently repairing such breaks. RecO, a protein that is essential for the extreme radioresistance of DR, is one of the major recombination ...
Jihee Hwang +6 more
doaj +1 more source
Acousto-microfluidics for screening of ssDNA aptamer [PDF]
Scientific Reports, 2016 AbstractWe demonstrate a new screening method for obtaining a prostate-specific antigen (PSA) binding aptamer based on an acoustofluidic separation (acoustophoreis) technique. Since acoustophoresis provides simultaneous washing and separation in a continuous flow mode, we efficiently obtained a PSA binding aptamer that shows high affinity without any ...
Park, Jee-Woong +5 more
openaire +3 more sources
iScience, 2022 Summary: Bacterial condensin preferentially loads onto single-stranded DNA (ssDNA) in vitro and onto rDNA in vivo to support proper chromosome compaction.
Koichi Yano +2 more
doaj +1 more source
eLife, 2019 APOBEC3G (A3G), an enzyme expressed in primates with the potential to inhibit human immunodeficiency virus type 1 (HIV-1) infectivity, is a single-stranded DNA (ssDNA) deoxycytidine deaminase with two domains, a catalytically active, weakly ssDNA binding ...
Michael Morse +5 more
doaj +1 more source
eLife, 2015 Escherichia coli single-stranded (ss)DNA binding (SSB) protein mediates genome maintenance processes by regulating access to ssDNA. This homotetrameric protein wraps ssDNA in multiple distinct binding modes that may be used selectively in different DNA ...
Sukrit Suksombat +4 more
doaj +1 more source