Results 151 to 160 of about 33,191 (261)
Abstract Single‐nucleotide polymorphisms (SNPs) may influence gene expression and contribute to interindividual variability in immune responses and disease susceptibility. Interleukin‐33 (IL33), a cytokine involved in inflammation, immune regulation, epithelial barrier homeostasis, and tissue remodeling, has been implicated in allergic, autoimmune ...
Aléia Harumi Uchibaba Yamanaka +5 more
wiley +1 more source
Beyond the alarm: unveiling the multifaceted role of IL-33 in kidney disease. [PDF]
Yang M, Miao S, Yu M, Fu X, Qin X.
europepmc +1 more source
Development of 2‑Methyl-5-phenylpyrrolidine-Based ST2 Inhibitors for Neuroinflammatory Conditions. [PDF]
Yuan X +13 more
europepmc +1 more source
ABSTRACT Early identification of refractory disease remains a significant unmet clinical need in patients with diffuse large B‐cell lymphoma (DLBCL). This scoping review was conducted to assess the current knowledge on the use of circulating tumor DNA (ctDNA), either alone or in combination with immune markers, as predictive tools for treatment outcome
Ailin McMahon +3 more
wiley +1 more source
RNAi targeting Myzus persicae (Hemiptera) stylet cuticle proteins reduces ZYMV transmission. [PDF]
Liang J +4 more
europepmc +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Metabolism in Tumor: Mechanisms and Therapeutic Perspectives
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng +6 more
wiley +1 more source

