Results 151 to 160 of about 34,767 (273)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, Volume 600, Issue 19, Page 2947-2960, October 2026.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, Volume 13, Issue 10, Page 2124-2133, October 2026.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 871-889, October 2026.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source

Non‐invasive biomarkers in biliary atresia: A scoping review of fibrosis assessment, translational readiness and clinical implementation gaps

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Biomarkers are positioned by their highest developmental stage. Most biomarkers remain in exploratory phases, with serum MMP‐7 and elastography showing the greatest translational maturity. This highlights the primary challenge is the transition from biomarker discovery to clinical implementation.
Elizabeth Brits, Stephen Brown, Lezelle Botes, Michael Pienaar   +3 more
wiley   +1 more source

ST2

Japanese Journal of Allergology, 2020
openaire   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng, Hanqing Zhang, Yun Wu, Song Chen   +3 more
wiley   +1 more source

Serum Soluble ST2

Journal of the American College of Cardiology, 2010
Weir, Robin A.P., Miller, Ashley M., Murphy, Grace E.J., Clements, Suzanne, Steedman, Tracey, Connell, John M.C., McInnes, Iain B., Dargie, Henry J., McMurray, John J.V.   +8 more
openaire   +1 more source

Analytical Framework for System‐Level Fragility Surfaces of Reinforced Concrete Bridges Under Mainshock‐Aftershock Sequences

Earthquake Engineering &Structural Dynamics, Volume 55, Issue 13, Page 3264-3284, 25 October 2026.
ABSTRACT Conventional single intensity measure (IM) fragility approaches with simplified component dependency assumptions overlook the progressive damage accumulation and evolving inter‐component correlations that govern system behavior under mainshock‐aftershock (MSAS) loading.
Muhammad Rashid, Mayuko Nishio
wiley   +1 more source

Targeting upstream alarmins (TSLP, IL-33, IL-25): a new frontier in treating type 2 chronic rhinosinusitis with nasal polyps. [PDF]

Front Immunol
Li S.
europepmc   +1 more source

ST2 promotes TOLerance [PDF]

Nature Reviews Immunology, 2004
openaire   +1 more source