Results 131 to 140 of about 34,767 (273)
Analysis of genomic alterations in ST1 and ST2.
(A) Comparison of the number of somatic nonsynonymous and splice site mutations. (B) Comparison of the number of CNV segments (upper panel) and CNV profiles (bottom panel) on chromosomes 17 and 12 between ST1 and ST2.
Yuki Yokota (267669) +11 more
core +1 more source
ABSTRACT Monitoring antimicrobial resistance (AMR) in fish pathogens is essential for supporting sustainable aquaculture. In this study, susceptibility testing and genome sequencing were used to characterize the AMR profile of seven Flavobacterium psychrophilum originating from Danish rainbow trout farms (2019–2022).
Valentina L. Donati, Lone Madsen
wiley +1 more source
DNA structures with short single‐strand gaps in the non‐template strand of the T7 promoter prevent transcription by T7 RNA polymerase. Contrary to intuition, however, transcriptional activity can be observed again when the size of the gap increases toward the transcription start site, thereby reducing the proportion of double‐stranded DNA in the ...
Michael W. Haydell +2 more
wiley +2 more sources
ST2, a member of the Toll/IL-1R superfamily, negatively regulates both TLR2 and TLR4 signaling. In this study, we report that ST2-deficient mice were more susceptible to polymicrobial sepsis than their wild-type littermates, with increased production of ...
Siobhan Blankson +7 more
core +1 more source
A Personalized Recovery Intervention to Support Sleep Health in Emergency Healthcare Professionals
ABSTRACT Optimizing sleep health in healthcare professionals is a challenge, as misalignment between endogenous circadian rhythms and exogenous work schedules undermines recovery, well‐being, and performance. This study evaluated a tailored recovery intervention based on cognitive‐behavioural approaches for insomnia designed to support recovery to ...
Laura Schmidt +8 more
wiley +1 more source
Understanding exosomes in regenerative dentistry
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
ABSTRACT Introduction Childhood tuberculosis (TB) remains a significant global health challenge, with a substantial number of cases going undiagnosed, particularly among children under five. Early diagnosis and intervention are crucial to reduce TB‐associated morbidity and mortality.
Julia van den Brink +8 more
wiley +1 more source
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin +6 more
wiley +1 more source
BackgroundHypertrophic Cardiomyopathy (HCM) is an inherited heart disease and the pathogenesis of HCM involves genetic mutations, hemodynamic stress, and metabolic factors, with myocardial fibrosis playing a crucial role in severe clinical events.
Xingyu Cao +7 more
doaj +1 more source

