Results 131 to 140 of about 30,785 (250)

ST2/IL-33 axis blockade inhibits regulatory T cell cytotoxicity towards CD8 T cells in the leukemic niche

Nature Communications
Acute myeloid leukemia (AML) patients present with CD8 exhaustion signatures, and pharmacologic inhibition of checkpoints can have therapeutic benefit. The alarmin IL-33 and its receptor STimulation-2 (ST2) promote activation of tissue-regulatory T cells
Hua Jiang, Denggang Fu, Santhosh Kumar Pasupuleti, Baskar Ramdas, Alan Long, Abdulraouf M. Ramadan, Jinfeng Yang, Ramesh Kumar, Jessica H. Hartman, B. Jacob Kendrick, Ed Simpson, Hongyu Gao, Yunlong Liu, Drew Moore, Suganya Subramanian, Stefano Berto, Anilkumar Gopalakrishnapillai, Sonali P. Barwe, Hongfen Guo, Nai-Kong V. Cheung, Reuben Kapur, Sophie Paczesny   +21 more
doaj   +1 more source

Phenotypic Florfenicol Resistance in floR‐Harbouring Flavobacterium psychrophilum Isolates (CC‐ST90): A Case Study From Danish Freshwater Rainbow Trout Aquaculture

Journal of Fish Diseases, EarlyView.
ABSTRACT Monitoring antimicrobial resistance (AMR) in fish pathogens is essential for supporting sustainable aquaculture. In this study, susceptibility testing and genome sequencing were used to characterize the AMR profile of seven Flavobacterium psychrophilum originating from Danish rainbow trout farms (2019–2022).
Valentina L. Donati, Lone Madsen
wiley   +1 more source

SUPPRESSION OF TUMORIGENICITY-2 (ST2), TROPONIN-I DAN KOMBINASI ST2 DAN TROPONIN-I SEBAGAI STRATIFIKASI RISIKO PAYAH JANTUNG. Kajian Pada Pasien Infark Miokard Akut [PDF]

, 2015
SUPPRESSION OF TUMORIGENICITY-2 (ST2), TROPONIN-I DAN KOMBINASI ST2 DAN TROPONIN-I SEBAGAI STRATIFIKASI RISIKO PAYAH JANTUNG. Kajian Pada Pasien Infark Miokard Akut INTISARI Laily Shofiyah, J.B. Suparyatmo, B.
Shofiyah, Laily
core  

The cold case of state transition 7 (stt7) mutants of Chlamydomonas reinhardtii, solved by whole‐genome sequencing

New Phytologist, EarlyView.
Long‐read whole‐genome sequencing revealed extensive chromosomal rearrangements and aneuploidy in a widely used Chlamydomonas reinhardtii stt7‐1 mutant. The STT7 gene (shown in red) was found to be split between two rearranged chromosomes, providing a molecular explanation for the long‐standing failure of this mutant in genetic crosses.
Sandrine Bujaldon, Adrien Burlacot, Frédéric Chaux, Francis‐André Wollman   +3 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

A Triassic chronostratigraphic and palaeogeographic framework for the Utsira High area, northern North Sea: Reconstructing a basin‐scale drainage divide

Sedimentology, EarlyView.
ABSTRACT The Triassic succession of the northern North Sea comprises a series of interbedded sandstones, mudstones and conglomerates deposited under a fluctuating arid to semi‐humid climate regime, which are often difficult to correlate regionally due to differing lithostratigraphic schemes and poor age control. Despite existing regional studies on the
Riccardo Sordi, Adrian Hartley, Shaan Heydenrych, Spyridon Saltapidas   +3 more
wiley   +1 more source

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential

Frontiers in Immunology
Interleukin-33 (IL-33) is a nuclear factor and member of the IL-1 cytokine family. IL-33 is mainly expressed by epithelial and endothelial cells and exerts its function through interaction with various immune cells, and binding to its receptor can form ...
Feiya Sheng, Mi Li, Jia-Mei Yu, Si-Yu Yang, Liang Zou, Guan-Jun Yang, Le-Le Zhang, Le-Le Zhang   +7 more
doaj   +1 more source

Implementability of Point‐of‐Care Ultrasound for Paediatric Tuberculosis Diagnosis in Resource‐Constrained Settings: Experiences and Perspectives From Uganda

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Childhood tuberculosis (TB) remains a significant global health challenge, with a substantial number of cases going undiagnosed, particularly among children under five. Early diagnosis and intervention are crucial to reduce TB‐associated morbidity and mortality.
Julia van den Brink, Martien Humblet, Emmanuel Nasinghe, Grace Paul Kisitu, Emmanual Tenywa, Rinn Song, Nora Engel, Francesca Wanda Basile, Else Margreet Bijker   +8 more
wiley   +1 more source

Fast Reconfigurable Optical Directed Logic Chip Using 2 × 2 Optical Switch on SOI Platform

Advanced Photonics Research, Volume 7, Issue 8, August 2026.
We demonstrated a compact and power‐efficient EO optical switch on silicon platform with microring resonators. The microring resonators are arranged with a strictly nonblocking crossbar architecture. Through detailed analysis and testing, this switch not only performs the function of switching routing but also realizes the function of several logic ...
Yuexin Yin, Shiyu Liao, Xinru Xu, Guoyan Zeng, Daming Zhang, Shiyoshi Yokoyama   +5 more
wiley   +1 more source

Practice, knowledge and attitude of physicians and pharmacists towards the spontaneous reporting system of adverse drug reactions in Switzerland

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2797-2808, August 2026.
Introduction Introduction Reporting adverse drug reactions (ADRs) is essential for detecting drug risks. Despite legal obligations in Switzerland, underreporting remains an issue. This study assessed practice, knowledge and attitudes towards the spontaneous ADR reporting system among physicians and pharmacists.
Fiona A. Strobel, Thomas Stammschulte, Patrick E. Beeler   +2 more
wiley   +1 more source