Results 121 to 130 of about 34,767 (273)

Expression of interleukin-33 and its receptor ST2 in periapical granulomas and radicular cysts

, 2016
BACKGROUND: Interleukin-33 (IL-33) is a recently identified cytokine belonging to the IL-1 family and ligand for the IL-1 receptor-related protein ST2. IL-33/ST2 signaling plays a critical role in allergy, autoimmunity, and chronic inflammatory disorders,
Pejnović, Nada, Velicković, Milena, Jeftić, Ilija, Lukić, Aleksandra, Petrović, Renata, Mitrović, Slobodanka, Kanjevac, Tatjana   +6 more
core   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Technology Matters: Ambient voice technology in mental health and neurodevelopmental settings – considerations for responsible implementation and evidence gaps

Child and Adolescent Mental Health, EarlyView.
Documentation comprises a large proportion of Child and Adolescent Mental Health Service (CAMHS) clinicians/practitioners' work burden and is often completed outside contracted working hours, either requiring overtime pay and/or contributing to burnout.
Judith Dineley, Noah Stanton, Aadam Aziz, Matteo Catanzano, Hissah Al Abdulsalam, Huajie Jin, Nicholas Cummins, Salim Jakhra, Solomon Wong, Johnny Downs   +9 more
wiley   +1 more source

ST2 Análise e Equações com Derivadas Parciais

, 2019
ST2 - Análise e Equações com Derivadas Parciais ...
Soares, Ana
core  

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Atherosclerosis severity is not affected by a deficiency in IL‐33/ST2 signaling

, 2015
Interleukin (IL)-33 is a cytokine of the IL-1 family, which signals through the ST2 receptor. Previous work demonstrated that the systemic administration of recombinant IL-33 reduces the development of atherosclerosis in apolipoprotein E-deficient (ApoE(-
Rodriguez, Emiliana, Mean, Isabelle, Praxedis Martin, Gabay, Cem, Emiliana Rodriguez, Woldt, Estelle, Estelle Woldt, Cem Gabay, Palmer-Lourenco, Gaby, Isabelle Mean, James, Richard William, Gaby Palmer, Richard W. James, Kwak, Brenda, Brenda R. Kwak, Smith, Dirk E, Martin, Praxedis Sina, Dirk E. Smith, Rodriguez E, James RW, Smith DE, Martin P, Woldt E, Mean I, Gabay C, Palmer G, Kwak BR   +26 more
core   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source

Correlation Profile of Suppression of Tumorigenicity 2 and/or Interleukin-33 with Biomarkers in the Adipose Tissue of Individuals with Different Metabolic States

Diabetes, Metabolic Syndrome and Obesity, 2020
Amal Hasan,1 Shihab Kochumon,1 Ebaa Al-Ozairi,2,3 Jaakko Tuomilehto,4– 6 Fahd Al-Mulla,7 Rasheed Ahmad1 1Department of Immunology and Microbiology, Dasman Diabetes Institute, Kuwait City, Kuwait; 2Clinical Research Unit, Medical Division, Dasman ...
Hasan A, Kochumon S, Al-Ozairi E, Tuomilehto J, Al-Mulla F, Ahmad R   +5 more
doaj  

Le ST2: nouveau marqueur de fibrose

, 2016
Review sur le ST2, un nouveau marqueur de fibrose ...
LE GOFF, Caroline
core  

Hyperactivity in context: comparing actigraphy and informant ratings across the school week

Journal of Child Psychology and Psychiatry, EarlyView.
Background Hyperactivity is a core symptom of childhood attention deficit hyperactivity disorder (ADHD), yet no population‐based studies have compared objective and subjective hyperactivity measures across the school day. Methods This study used data from N = 6,518 seven‐year‐olds in the Millennium Cohort Study.
Anna Morris, David M. Howard, Adam Shortland, Linglong Qian, Zina Ibrahim, Jonathan Hind, Laurence Telesia, Faith Matcham, Edmund Sonuga‐Barke, Johnny Downs   +9 more
wiley   +1 more source