Results 111 to 120 of about 22,553 (226)

Chinese Position Paper on Biologic Therapy for Allergic Rhinitis

Allergy, Volume 81, Issue 5, Page 1354-1369, May 2026.
ABSTRACT Allergic rhinitis (AR) is a common, persistent nasal disorder that poses significant public health challenges worldwide. Current treatment options frequently fail to achieve adequate symptom control in a substantial subset of patients. Over the past two decades, biologic therapies that target type 2 inflammatory pathways have been used to ...
Yuan Zhang, Jingyun Li, Xian Li, Menglin Wang, Xiangli Yang, Li Shi, Zhiwei Cao, Yan Feng, Weiwei Liu, Zhendong Xu, Ruixia Ma, Xiaoping Gao, Wen Liu, Jinmei Xue, Xiaoyong Ren, Xuezhong Li, Xicheng Song, Yi Yang, Fang Quan, Lei Cheng, Weihong Jiang, Huabin Li, Jian Li, Huanhai Liu, Jianfeng Liu, Zheng Liu, Wei Lv, Qianhui Qiu, Xiangdong Wang, Yu Xu, Yuanteng Xu, Qintai Yang, Yucheng Yang, Jing Ye, Hongmeng Yu, Dongdong Zhu, Chengshuo Wang, Luo Zhang   +37 more
wiley   +1 more source

Patterns and Clinical Efficacy of Biologics Switching in Patients With Severe Asthma: A Systematic Review and Meta‐Analysis

Allergy, Volume 81, Issue 5, Page 1548-1570, May 2026.
This meta‐analysis included 2292 patients with severe asthma who underwent biologic switching across 23 countries/regions. The most prevalent switching pattern was from mepolizumab to benralizumab, with suboptimal asthma control being the primary reason.
Yang Zheng, Ya‐chun Li, Sheng‐jie Li, Meng Xu, Jia‐qian Hu, Wen‐qu Tian, Shi‐wei Chen, Xue‐hui Li, Ying He, Gan Lu, Mübeccel Akdis, Ioana Agache, Cezmi A. Akdis, Ya‐dong Gao   +13 more
wiley   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, Volume 14, Issue 4, Page 1002-1016, May 2026.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

A panel of ST2, Reg3α, Elafin, and TNFR1: Predictive value for acute GvHD and outcomes in hematological malignancy patients post allo-HSCT. [PDF]

Medicine (Baltimore)
Hao Q, Liu X, Li T, Wei W, Qi T, Zhang S, Fei X, Gu J, Wang J.   +8 more
europepmc   +1 more source

Editorial Perspective: A call for action on imposter participants in child and adolescent mental health research

Child and Adolescent Mental Health, Volume 31, Issue 2, Page 149-152, May 2026.
Imposter participants are dishonest participants who fake their identities or exaggerate their experiences to participate in research. This appears to be a rising problem in quantitative and qualitative research as well as lived experience groups for child and adolescent mental health research.
Brian C.F. Ching, Cornelius Ani, Angie Pitt, Sharon Eager, Emily Simonoff, Johnny Downs   +5 more
wiley   +1 more source

Transcriptomic and Proteomic Analyses Show Minimal Role for ST2 on MCPT5-Expressing Mast Cells in Primary Heligmosomoides polygyrus bakeri Infection. [PDF]

Parasite Immunol
Ong NWP, Hodge SH, Baker CP, Smyth DJ, Frangova T, McSorley HJ.   +5 more
europepmc   +1 more source

Fetal Fraction Signatures: A Quality Control Tool to Detect Potentially Confounding Situations in NonInvasive Prenatal Diagnosis of Monogenic Conditions

Clinical Genetics, Volume 109, Issue 5, Page 869-875, May 2026.
Noninvasive prenatal diagnosis for monogenic diseases (NIPD‐M) to detect inherited mutations is performed in parallel with fetal fraction signatures, to detect various anomalies that may compromise diagnosis. An extra regression analysis may be necessary to resolve mosaic situations. ABSTRACT Noninvasive prenatal diagnosis relies on the analysis of the
Jean‐Louis Blouin, Claudine Rieubland, Thierry Nouspikel   +2 more
wiley   +1 more source

IL-33 promotes transcriptional and metabolic adaptations of tissue-resident Th2 cells. [PDF]

J Immunol
Kania AK, Sanin DE, Gu X, Gidley M, Kokosinski E, Smith A, Pearce E, Pearce EJ.   +7 more
europepmc   +1 more source

A call to action: A consensus statement on knowledge gaps and research priorities on the management of women with early onset type 2 diabetes in the preconception, pregnancy and postnatal periods

Diabetic Medicine, Volume 43, Issue 5, May 2026.
Abstract Aims Research to inform, co‐develop and evaluate optimal care for women with early‐onset type 2 diabetes (EOT2D) before, during and after pregnancy is lacking. Informed by patient perspectives and the results of the James Lind Alliance priority‐setting partnership in diabetes in pregnancy, we aimed to develop a consensus statement to guide ...
Sara L. White, Danielle Schoenaker, Sharon Mackin, Rita Forde, Angela C. Flynn, Eleanor Dyer, Nicola Heslehurst, Robert Lindsay, Claire L. Meek   +8 more
wiley   +1 more source

Structures of clinical antibodies bound to IL-33 uncover two distinct epitopes underlying differential efficacy. [PDF]

MAbs
Chen J, Wang Y, Wang X.
europepmc   +1 more source