Results 91 to 100 of about 34,767 (273)

Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation

Rheumatology &Autoimmunity, EarlyView.
The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang, Rongyuan Gao, Zhaohui Zheng   +2 more
wiley   +1 more source

The potential role of IL-33/ST2 pathway in renal allograft rejection

, 2019
Interleukin (IL)-33 IL-1 cytokine . IL-33 suppression of tumorigenicity 2 (ST2)
Mi-Yeon Yu
core  

IL-33/ST2 axis controls Th2/IL-31 and Th17 immune response in allergic airway diseases

, 2015
IL-33 targeting ST2 receptor (T1/ST2), expressed on Th2 cell surface, regulates the production of cytokines like IL-17A and IL-31.We studied the role of IL-33/ST2 axis in IL-31 and IL-17A production in patients with allergic rhinitis (AR) and with ...
M. Profita, A. Bonanno, L. Riccobono, C. G. Uasuf, L. Vocca, A. Sala, S. Gangemi, G. D. Albano, C. Di Sano, R. Gagliardo, Vocca, Lavinia, Profita, Mirella, Di Sano, Caterina, Sala, Angelo, GANGEMI, Sebastiano, Uasuf, Carina G., BONANNO, Anna Maria, Gagliardo, Rosalia, Albano, Giusy Daniela, Riccobono, Loredana   +19 more
core   +1 more source

ST2/MyD88 deficiency protects mice against aGVHD and spares T-regulatory cells

, 2020
Acute graft-versus-host disease (aGVHD) hinders the efficacy of allogeneic hematopoietic cell transplantation (HCT). Plasma levels of soluble membrane-bound ST2 (ST2) are elevated in human and murine aGVHD and correlated to type 1 T cells response.
Zhang, Jilu, Paczesny, Sophie, Ramadan, Abdulraouf M., Griesenauer, Brad, Yang, Jinfeng, Campa, Khaled, Egbosiuba, Jane, Jiang, Hua   +7 more
core   +1 more source

Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation

Respirology, EarlyView.
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley   +1 more source

Fixing Ill‐Formed UTF‐16 Strings With SIMD Instructions

Software: Practice and Experience, EarlyView.
ABSTRACT Background We must fix ill‐formed UTF‐16 strings, where surrogate pairs are mismatched. Programming languages such as JavaScript provide functions that replace mismatched surrogates with the Unicode replacement character (U + FFFD). Objectives We seek to accelerate the correction of ill‐formed UTF‐16 strings.
Robert Clausecker, Daniel Lemire
wiley   +1 more source

Involvement of PU.1 in Mast Cell/Basophil-Specific Function of the Human IL1RL1/ST2 Promoter

Allergology International, 2012
Background: The human IL1RL1/ST2 gene encodes IL33 receptor. Recently, IL33 has been recognized as a key molecule for the development of Th2 response. Although mast cells and basophils are major targets of IL33 and play important roles in IL33-mediated ...
Yosuke Baba, Keiko Maeda, Takuya Yashiro, Eisuke Inage, Frangois Niyonsaba, Mutsuko Hara, Ryuyo Suzuki, Yoshikazu Ohtsuka, Toshiaki Shimizu, Hideoki Ogawa, Ko Okumura, Chiharu Nishiyama   +11 more
doaj   +1 more source

ST2 regulates bone loss in a site‐dependent and estrogen‐dependent manner

, 2018
Interleukin-33 (IL-33) and its receptor, ST2, are implicated in bone remodeling. The lack of estrogen after menopause results in an accelerated bone loss. Here we investigated the role of ST2 in the bone loss induced by estrogen deficiency. ST2-deficient
Izabella L. A. Lima, Soraia Macari, Tarcília Aparecida da Silva, George J. Dias, Garlet, Gustavo P., Tarcília A. Silva, Dias, George J., Mila Fernandes Moreira Madeira, George J Dias, Sandra Yasuyo Fukada, Rafael Scaf de Molon, Rafael S. de Molon, Thaís S. F. Pereira, Molon, Rafael S. de [UNESP], Mauro M. Teixeira, Cirelli, Joni A. [UNESP], Gustavo P. Garlet, Izabella Lucas de Abreu Lima, Silva, Tarcilia A., Mauro Martins Teixeira, Thaís dos Santos Fontes Pereira, Madeira, Mila F. M., Mila F. M. Madeira, Joni Augusto Cirelli, Raphael E. Szawka, Macari, Soraia, Pereira, Thais S. F., Szawka, Raphael E., Gustavo Pompermaier Garlet, Joni A. Cirelli, Fukada, Sandra Y., Lima, Izabella L. A., Sandra Y. Fukada, Teixeira, Mauro M., Raphael Escorsim Szawka   +34 more
core   +1 more source

A method for determining the performance of formulas for calculating the crack width and spacing in reinforced concrete elements

Structural Concrete, EarlyView.
Abstract Numerous studies have been conducted to determine the performance of formulas for calculating crack width and spacing in reinforced concrete structures. Generally, these studies pay limited attention to the application areas of those formulas and how to compare different representations of the crack width and spacing.
Anton van der Esch, Rob Wolfs, Simon Wijte   +2 more
wiley   +1 more source

IL-33 and ST2 in Allergic Asthma. [PDF]

, 2013
Although our understanding of the pathogenesis of asthma remains limited, data now indicate that most patients with asthma have an immune-mediated component.
Nguyen, Tammie
core   +1 more source