Results 81 to 90 of about 33,191 (261)

Variations in trajectories of emotional and behavioural symptoms in children and young people with pre‐existing mental health and neurodevelopmental conditions before and during the COVID‐19 pandemic: A nested data linkage clinical cohort study

JCPP Advances, EarlyView.
Abstract Background Children and young people with pre‐existing mental health and neurodevelopmental conditions may have experienced heterogeneous mental health impacts during the COVID‐19 pandemic, but what facts may explain these variations are still unclear. We aimed to examine variations in the longitudinal trajectories of emotional and behavioural
Brian C. F. Ching, Alice Wickersham, Dominic Stringer, Sarjhana Ragunathan Brindha, Craig Colling, Ruby Morton, Valeria Parlatini, Johnny Downs, Emily Simonoff   +8 more
wiley   +1 more source

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

AC1-ST2 - Japanese

Japanese Archival tape notes: 45.00 End of Tape ST2, side 1. Tape ST2, side 2. 61.15 End of Tape ST2, side 2 and end of archive tape. AIATSIS Identifier: A16771.

core   +1 more source

IL-33 and ST2 levels in chronic kidney disease: Associations with inflammation, vascular abnormalities, cardiovascular events, and survival.

PLoS ONE, 2017
ObjectiveIncreased inflammation, associated with the increase in chronic kidney disease (CKD) stage, has a very important influence in vascular injury and cardiovascular diseases.
Ozkan Gungor, Hilmi Umut Unal, Aydin Guclu, Mustafa Gezer, Tayfun Eyileten, Fatma Betül Guzel, Orcun Altunoren, Ertugrul Erken, Yusuf Oguz, Ismail Kocyigit, Mahmut Ilker Yilmaz   +10 more
doaj   +1 more source

Association of soluble ST2 with all-cause and cardiovascular mortality in renal transplant recipients: a single-centre cohort study

BMC Nephrology, 2020
Background Soluble ST2 is a novel biomarker of myocardial fibrosis with an established role in prognostication of patients with heart failure. Its role in cardiovascular risk prediction for renal transplant recipients has not been investigated despite ...
Paul A. Devine, Christopher Cardwell, Alexander P. Maxwell   +2 more
doaj   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

IL-33/ST2 axis promotes mast cell survival via BCLXL [PDF]

, 2014
Mast cells (MC) are potent innate immune cells that accumulate in chronically inflamed tissues. MC express the IL-33 receptor IL-1 receptor-related protein ST2 at high level, and this IL-1 family cytokine both activates MC directly and primes them to ...
NC DOCKS at The University of North Carolina at Greensboro, Kepley, Christopher   +1 more
core  

Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of Staphylococcus aureus-Induced Septic Arthritis

Frontiers in Immunology, 2018
The ST2 receptor is a member of the Toll/IL-1R superfamily and interleukin-33 (IL-33) is its agonist. Recently, it has been demonstrated that IL-33/ST2 axis plays key roles in inflammation and immune mediated diseases. Here, we investigated the effect of
Larissa Staurengo-Ferrari, Silvia C. Trevelin, Silvia C. Trevelin, Victor Fattori, Daniele C. Nascimento, Kalil A. de Lima, Jacinta S. Pelayo, Florêncio Figueiredo, Rubia Casagrande, Sandra Y. Fukada, Mauro M. Teixeira, Thiago M. Cunha, Foo Y. Liew, Rene D. Oliveira, Paulo Louzada-Junior, Fernando Q. Cunha, José C. Alves-Filho, Waldiceu A. Verri   +17 more
doaj   +1 more source

Integrating Grain to Ground Motion Data for Critical Rock Bridge and Slope Failure Analysis

International Journal for Numerical and Analytical Methods in Geomechanics, EarlyView.
ABSTRACT Rock masses can fail catastrophically with little warning, yet their stability depends on hidden internal connections that channel forces and localise damage. Among these, rock bridges–a “known unknown” in slope mechanics–lock fractured rock and control how failure unfolds, but their concealed geometry and uncertain strength obscure where and ...
Antoinette Tordesillas, Shuo Zhou, Leonnardo Probst, Pat Bellett, Michal Nitka, Jacek Tejchman   +5 more
wiley   +1 more source