Results 81 to 90 of about 34,767 (273)
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
Medicinal Research Reviews, EarlyView.ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
PLoS ONE, 2017 ObjectiveIncreased inflammation, associated with the increase in chronic kidney disease (CKD) stage, has a very important influence in vascular injury and cardiovascular diseases.
Ozkan Gungor +10 more
doaj +1 more source
ST2 deficiency attenuates K/BxN arthritis.
, 2013 Arthritis was initiated in ST2−/− mice and their WT littermates via intraperitoneal administration of K/BxN mouse serum on days 0 and 2 (n = 5/group).
Jun-Xia Wang (303319) +7 more
core +1 more source
ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii
mLife, EarlyView.Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei +7 more
wiley +1 more source
IL-33/ST2 axis promotes mast cell survival via BCLXL [PDF]
, 2014 Mast cells (MC) are potent innate immune cells that accumulate in chronically inflamed tissues. MC express the IL-33 receptor IL-1 receptor-related protein ST2 at high level, and this IL-1 family cytokine both activates MC directly and primes them to ...
NC DOCKS at The University of North Carolina at Greensboro +1 more
core
Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential
Phytotherapy Research, EarlyView.Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi +5 more
wiley +1 more source
IL-33/ST2 axis in innate and acquired immunity to tumors
, 2012 Interleukin-33, a ligand for ST2/T1, has an important role in allergy, autoimmunity and inflammation. The role of IL-33/ST2 axis in cancer is not elucidated.
Pejnović, Nada +4 more
core +1 more source
BMC Nephrology, 2020 Background Soluble ST2 is a novel biomarker of myocardial fibrosis with an established role in prognostication of patients with heart failure. Its role in cardiovascular risk prediction for renal transplant recipients has not been investigated despite ...
Paul A. Devine +2 more
doaj +1 more source