Results 61 to 70 of about 33,191 (261)

Early synovial regulatory T cell engagement in posttraumatic osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang, Mingde Cao, Jianting Li, Bruma Sai‐Chuen Fu, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung   +5 more
wiley   +1 more source

IL-33 and ST2 in Allergic Asthma. [PDF]

, 2013
Although our understanding of the pathogenesis of asthma remains limited, data now indicate that most patients with asthma have an immune-mediated component.
Nguyen, Tammie
core   +1 more source

ASS1 Promotes Atherosclerotic Inflammation Through the NLRP3/IL-33/ST2 Axis in Ox-LDL–Induced Foam Cells

Frontiers in Bioscience-Landmark
Background: Atherosclerosis is a chronic inflammatory disease characterized by lipid-driven immune dysregulation. Argininosuccinate synthase 1 (ASS1) has been implicated in macrophage inflammation, yet its precise mechanistic role in ...
Shaoyu Wu, Feihuang Han, Zheng Qiao, Sheng Yuan, Xiaohui Bian, Bin Zhang, Kefei Dou, Dunliang Ma   +7 more
doaj   +1 more source

Allograft or Recipient ST2 Deficiency Oppositely Affected Cardiac Allograft Vasculopathy via Differentially Altering Immune Cells Infiltration

Frontiers in Immunology, 2021
The role of IL-33/ST2 signaling in cardiac allograft vasculopathy (CAV) is not fully addressed. Here, we investigated the role of IL-33/ST2 signaling in allograft or recipient in CAV respectively using MHC-mismatch murine chronic cardiac allograft ...
Zhenggang Zhang, Na Zhang, Junyu Shi, Chan Dai, Suo Wu, Mengya Jiao, Xuhuan Tang, Yunfei Liu, Xiaoxiao Li, Yong Xu, Zheng Tan, Zheng Tan, Feili Gong, Fang Zheng, Fang Zheng   +14 more
doaj   +1 more source

The synergistic impact of granulocytic myeloid‐derived suppressor cells and innate lymphoid cells in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by immune dysregulation and fibrosis, with myeloid‐derived suppressor cells (MDSCs) emerging as important regulators of immune responses. However, the role of MDSCs in SSc‐associated fibrosis and their interactions with other immune cell populations remain poorly ...
Stefanie Weber, Mario R. Angeli, Hashem Mohammadian, Hannah Labinsky, Maria Gabriella Raimondo, Richard Demmler, Yuko Ariza, Thomas Wohlfahrt, Markus Luber, Yi‐Nan Li, Jörg H.W. Distler, Tobias Bäuerle, Georg Schett, Simon Rauber, Andreas Ramming, Alina M. Ramming   +15 more
wiley   +1 more source

ST2 deficiency attenuates K/BxN arthritis.

, 2013
Arthritis was initiated in ST2−/− mice and their WT littermates via intraperitoneal administration of K/BxN mouse serum on days 0 and 2 (n = 5/group).
Jun-Xia Wang (303319), Richard T. Lee (303327), Nadia Fishgal (303323), Ruslan Shnayder (303321), Shinjiro Kaieda (303317), Richard L. Stevens (303328), Hillary Hei (303324), Peter A. Nigrovic (303330)   +7 more
core   +1 more source

Multi-Marker Strategy in Heart Failure: Combination of ST2 and CRP Predicts Poor Outcome. [PDF]

PLoS ONE, 2016
Natriuretic peptides (BNP and NT-proBNP) are recognized as gold-standard predictive markers in Heart Failure (HF). However, currently ST2 (member of the interleukin 1 receptor family) has emerged as marker of inflammation, fibrosis and cardiac stress. We
Anne Marie Dupuy, Corentin Curinier, Nils Kuster, Fabien Huet, Florence Leclercq, Jean Marc Davy, Jean Paul Cristol, François Roubille   +7 more
doaj   +1 more source

Generalized Beth–Uhlenbeck Entropy Formula From the Φ‐Derivable Approach

Contributions to Plasma Physics, EarlyView.
ABSTRACT We derive a generalized Beth–Uhlenbeck formula for the entropy of a dense fermion system with strong two‐particle correlations, including scattering states and bound states. We work within the Φ‐derivable approach to the thermodynamic potential.
David Blaschke, Gerd Röpke, Gordon Baym
wiley   +1 more source

ST2/IL-33 signaling in cardiac fibrosis

, 2019
Cardiac fibrosis is a significant global health problem associated with nearly all forms of heart disease. In the heart interstitial fibrosis may be reparative, replacing areas damaged by myocyte loss after acute infarction, or compensative, responding ...
Luigi Frati, Lorenza Tacchini, Elena Vianello, Massimiliano Marco Corsi Romanelli, Elena Dozio   +4 more
core   +1 more source

ST2-driven stimulation of basophils promotes a unique inflammatory profile in which basophil-derived CXCL1 is functionally important in their involvement in ADTI.

, 2020
(A–C) BMBs from C57BL/6J mice were activated with IgE/DNP or different doses of mIL-33. Gene expression 4 hours after activation was analyzed by microarray (A) and real time RT-PCR (B, C).
Rebecca Krier-Burris (8308524), Krishan D. Chhiba (8308521), Chia-Lin Hsu (58761), Shweta Hosakoppal (8308527), Sergejs Berdnikovs (315951), Mendy L. Miller (8308530), Paul J. Bryce (8308533)   +6 more
core   +1 more source