Results 41 to 50 of about 22,553 (226)

Allograft or Recipient ST2 Deficiency Oppositely Affected Cardiac Allograft Vasculopathy via Differentially Altering Immune Cells Infiltration

Frontiers in Immunology, 2021
The role of IL-33/ST2 signaling in cardiac allograft vasculopathy (CAV) is not fully addressed. Here, we investigated the role of IL-33/ST2 signaling in allograft or recipient in CAV respectively using MHC-mismatch murine chronic cardiac allograft ...
Zhenggang Zhang, Na Zhang, Junyu Shi, Chan Dai, Suo Wu, Mengya Jiao, Xuhuan Tang, Yunfei Liu, Xiaoxiao Li, Yong Xu, Zheng Tan, Zheng Tan, Feili Gong, Fang Zheng, Fang Zheng   +14 more
doaj   +1 more source

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

Animal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu, Jiaqi Chen, Zhonghui Li, Jiamin Zhou, Hui Zhang, Yujia Yu, Feng Cheng, Jie Bao, Chunhan Feng, Xiangqu Yu, Zhao Xia, Rao Ding, Xiang Li   +12 more
wiley   +1 more source

Correlation of serum ST2 levels with severity of diastolic dysfunction on echocardiography and findings on cardiac MRI in patients with heart failure with preserved ejection fraction

Indian Heart Journal, 2022
Objective: The aim of the present study was to find a correlation of serum Suppression of tumorigenicity 2 (ST2) levels with severity of diastolic dysfunction on echocardiography and cardiac magnetic resonance imaging (CMRI) in heart failure with ...
Vivek Agrawal, Suhas Hardas, Hasmukh Gujar, Deepak S. Phalgune   +3 more
doaj   +1 more source

Multi-Marker Strategy in Heart Failure: Combination of ST2 and CRP Predicts Poor Outcome. [PDF]

PLoS ONE, 2016
Natriuretic peptides (BNP and NT-proBNP) are recognized as gold-standard predictive markers in Heart Failure (HF). However, currently ST2 (member of the interleukin 1 receptor family) has emerged as marker of inflammation, fibrosis and cardiac stress. We
Anne Marie Dupuy, Corentin Curinier, Nils Kuster, Fabien Huet, Florence Leclercq, Jean Marc Davy, Jean Paul Cristol, François Roubille   +7 more
doaj   +1 more source

Practice, knowledge and attitude of physicians and pharmacists towards the spontaneous reporting system of adverse drug reactions in Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Introduction Introduction Reporting adverse drug reactions (ADRs) is essential for detecting drug risks. Despite legal obligations in Switzerland, underreporting remains an issue. This study assessed practice, knowledge and attitudes towards the spontaneous ADR reporting system among physicians and pharmacists.
Fiona A. Strobel, Thomas Stammschulte, Patrick E. Beeler   +2 more
wiley   +1 more source

ASS1 Promotes Atherosclerotic Inflammation Through the NLRP3/IL-33/ST2 Axis in Ox-LDL–Induced Foam Cells

Frontiers in Bioscience-Landmark
Background: Atherosclerosis is a chronic inflammatory disease characterized by lipid-driven immune dysregulation. Argininosuccinate synthase 1 (ASS1) has been implicated in macrophage inflammation, yet its precise mechanistic role in ...
Shaoyu Wu, Feihuang Han, Zheng Qiao, Sheng Yuan, Xiaohui Bian, Bin Zhang, Kefei Dou, Dunliang Ma   +7 more
doaj   +1 more source

ST2 gene products critically contribute to cellular transformation caused by an oncogenic Ras mutant

Heliyon, 2017
The ST2 gene was originally identified as a primary responsive gene, and the expressions of its gene products are induced by stimulation with growth factors and by oncogenic stresses.
Kenji Tago, Satoshi Ohta, Masaki Kashiwada, Megumi Funakoshi-Tago, Jitsuhiro Matsugi, Shin-ichi Tominaga, Ken Yanagisawa   +6 more
doaj   +1 more source

Application of influence diagrams to multi‐objective allocation of firefighting resources in process plants

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Identification of firefighting strategies (i.e., which endangered units to suppress or cool first) in chemical and process plants falls under the domain of multi‐objective decision‐making (MODM), where not only the safety and integrity of the affected process plant but also the safety of on‐site and off‐site vulnerable targets matter.
Sina Khakzad, Nima Khakzad
wiley   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Clinical and prognostic significance of biomarker ratios in patients with heart failure and concomitant atrial fibrillation and diabetes mellitus

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Heart failure (HF) in combination with atrial fibrillation (AF) and diabetes mellitus (DM) significantly worsens the prognosis of patients, increasing the risk of rehospitali­zations and mortality.
N.M. Kulaiets, V.M. Kulaiets
doaj   +1 more source