Results 231 to 240 of about 34,767 (273)
Some of the next articles are maybe not open access.
Clinica Chimica Acta, 2015
In addition to routine clinical laboratory tests (including natriuretic peptides and cardiac troponins), other biomarkers are gaining attention for their utility in heart failure (HF) management. Among them, soluble ST2 (sST2) a novel biomarker integrating inflammation, fibrosis, and cardiac stress has been included in the 2013 ACCF/AHA guideline for ...
Benjamin, Dieplinger, Thomas, Mueller
openaire +2 more sources
In addition to routine clinical laboratory tests (including natriuretic peptides and cardiac troponins), other biomarkers are gaining attention for their utility in heart failure (HF) management. Among them, soluble ST2 (sST2) a novel biomarker integrating inflammation, fibrosis, and cardiac stress has been included in the 2013 ACCF/AHA guideline for ...
Benjamin, Dieplinger, Thomas, Mueller
openaire +2 more sources
Soluble ST2—Analytical Considerations
The American Journal of Cardiology, 2015Suppression of tumorigenicity 2 (ST2, also known as interleukin [IL]-1 receptor-like-1) is an IL-1 receptor family member with transmembrane (ST2L) and soluble isoforms (sST2). ST2L is a membrane-bound receptor, and IL-33 is the functional ligand for ST2L.
Thomas, Mueller, Allan S, Jaffe
openaire +2 more sources
ST2 and Adrenomedullin in Heart Failure
Heart Failure Clinics, 2009ST2 is the receptor for interleukin-33, a cytokine with antihypertrophic and antifibrotic effects on the myocardium. Serum levels of the soluble form of ST2 serve as a biomarker for ventricular biomechanical strain and provide prognostic information in patients who have symptomatic heart failure. Adrenomedullin is a vasoactive peptide whose actions run
Rahul, Kakkar, Richard T, Lee
openaire +2 more sources
Molecular cloning of the chicken ST2 gene and a novel variant form of the ST2 gene product, ST2LV
Biochimica Et Biophysica Acta Gene Regulatory Mechanisms, 2004The ST2 gene encodes receptor-like molecules that are very similar to the interleukin-1 receptors. Three types of ST2 gene products, ST2, ST2L, and ST2V, can be produced by alternative splicing. In the course of cloning the chicken ST2 and ST2L cDNAs, we identified a novel variant cDNA other than ST2, ST2L, or ST2V, and tentatively named it ST2LV ...
Ken Yanagisawa +2 more
exaly +3 more sources
Soluble ST2 in Ventricular Dysfunction
2015Heart failure is a commonly encountered condition associated with increased morbidity, mortality, and healthcare cost. For years, its management has been strongly influenced by the use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide biomarkers. In some cases, this approach does not always identify patients with heart failure
Silvia, Lupu, Lucia, Agoston-Coldea
openaire +2 more sources
ST2 Testing for Chronic Heart Failure Therapy Monitoring: The International ST2 Consensus Panel
The American Journal of Cardiology, 2015Among patients with chronic heart failure (HF), it is known that soluble concentrations of the interleukin receptor family member ST2 (sST2) are prognostic for adverse outcome, including risk for progression of HF and death. Considerably less was known about the merits of serial testing of sST2 and whether such testing provides incremental information ...
James L, Januzzi +2 more
openaire +2 more sources
Soluble ST2 Testing in the General Population
The American Journal of Cardiology, 2015ST2 is a member of the interleukin (IL)-1 receptor family biomarker, and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress. Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in community-based populations free of cardiovascular disease.
Jennifer E, Ho +3 more
openaire +2 more sources
Identification of the product of the murine ST2 gene
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1993The murine ST2 gene is expressed in growth-stimulated BALB/c-3T3 cells. This gene encodes a protein that is similar to the extracellular portions of the interleukin-1 receptors (types 1 and 2). In this study, we prepared a polyclonal antibody against the recombinant ST2 protein produced in Escherichia coli.
T, Takagi +5 more
openaire +2 more sources
ST2: a novel biomarker for heart failure
Expert Review of Molecular Diagnostics, 2010ST2, an IL-1 receptor family member with transmembrane (ST2L) and soluble (sST2) isoforms, was originally described in the context of inflammatory and autoimmune diseases. However, after the identification of IL-33 as the functional ligand for ST2, and conceptualization of the role of ST2/IL-33 signaling in cardiac remodeling, sST2 has emerged as a ...
Anju, Bhardwaj, James L, Januzzi
openaire +2 more sources
Using ST2 in Cardiovascular Patients: A Review
Future Cardiology, 2014Biomarkers have emerged as indispensable tools for diagnosis and prognostication in a variety of cardiovascular diseases, and several are now standard of care. New markers are constantly being developed, but few are able to significantly improve upon already established markers.
Lori B, Daniels, Antoni, Bayes-Genis
openaire +2 more sources