Results 91 to 100 of about 4,650,966 (303)

Coordination Chemistry of U(Ⅵ) and N-tris(2-aminoethyl)amino-N',N',N'',N'',N''',N'''-hexaacetic Acid in Aqueous Solution

Yuanzineng kexue jishu
Uranium, as one of the actinide metal elements with relatively high abundance in nature, its natural existence forms are of great significance for research on environmental and chemical behaviors.
LYU Yifei1, 2, ZHANG Qianci2, YANG Suliang2, ZHANG Yan2, LIU Qian2, WANG Chen2, , TIAN Guoxin2, 3,
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Gold(III) Complexes with 18-Crown-6, 1-Aza-18-Crown-6, and Cryptands 22 and 222: Stability and Structure

Inorganics
The growing demand for gold in various high-technology applications necessitates the development of efficient and selective methods for its recovery and analysis, which can be achieved using such macrocyclic ligands as crown esters and their aza ...
Daniil N. Yarullin, Olga I. Logacheva, Viktor V. Aleksandriiskii, Maksim N. Zavalishin, George A. Gamov   +4 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

On the stability of the constant relative risk aversion (CRRA) under high degrees of uncertainty [PDF]

, 2012
Growth models under uncertainty and constant relative risk aversion (CRRA) utility are fragile in explaining consumers’ choice, as equilibrium consumption is dependent on distributional assumptions.
Paya, Ivan, Perote, Javier, Paya, I., Niguez, Trino-Manuel, Ñíguez, T.-M., Peel, D., Perote, J., Peel, David   +7 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A Note on the Stability of the Cheeger Constant of N-gons

Journal of Convex Analysis, 2015
The regular N-gon provides the minimal Cheeger constant in the class of all N-gons with fixed volume. This result is due to a work of D. Bucur and I. Fragalà [A Faber-Krahn inequality for the Cheeger Constant of N-gons, J. of Geometric Analysis (2014)]. In this note, we address the stability of their result in terms of the L
M. Caroccia, R. Neumayer
openaire   +5 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Coordination Chemistry of Uranyl Ion with Citric Acid

Yuanzineng kexue jishu
Citric acid (H3Cit), which is an important intermediate chemical in the tricarboxylic acid cycle metabolism of organisms, widely presents in nature and also is added in food and other daily necessities.
LI Zhi1, ZHANG Yan1, NASEN Buyanri1, DING Qixiu1, YANG Suliang1, WANG Chen1, , TIAN Guoxin1, 2
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source