Results 101 to 110 of about 4,650,966 (303)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
MoleculesBicyclic peptides have attracted the interest of pharmaceutical companies because of their remarkable properties, putting them on a new path in medicine.
Alicja Lisowska +7 more
doaj +1 more source
Evaluation of Impacts of Adaptive Cruise Control on Mixed Traffic Flow [PDF]
This paper addresses the impacts of Adaptive (Intelligent) Cruise Control (ACC) laws on traffic flow. Semi-automated vehicles, such as ACC Vehicles, with the capability to automatically follow each other in the same lane, will coexist with manually ...
Xi Zou, David Levinson
core
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Stability studies of titanium–carboxylate complexes: A multi-method computational approach
Open ChemistryUnderstanding the stability of metal–ligand complexes is essential for advancing applications in environmental, industrial, and biomedical chemistry; however, titanium coordination systems remain underexplored, particularly with organic ligands of ...
Omar Abdalazeem A. +4 more
doaj +1 more source
Stability constant and thermodynamic parameters for ethylene diamin tetra acetate cobaltate
, 2012 Stability constant and thermodynamic parameters for ethylene diamin tetra acetate cobaltateStability constant and thermodynamic parameters for ethylene diamin tetra acetate ...
Siddig, Ali
core
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source