Results 51 to 60 of about 644,626 (265)
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Stability of surfaces with constant mean curvature [PDF]
The notion of stability for surfaces with constant mean curvature H used in this paper is not the appropriate one. It requires the second variation of area to be positive for all compactly supported variations, and not only for those that preserve volume. This is such a strong definition that with it round spheres are not stable [cf. \textit{J.
openaire +2 more sources
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Thermodynamic parameters of phenylglycine interaction with UO2 2+, La3+ and Zr4+
Phenylglycine interactions with (UO2 2+, La3+ and Zr4+) transition metal ions were studied at different ionic strengths and different temperature degrees applying Bjerrum’s method. The work determine and discuss both the thermodynamic stabilities and the
Farid I. El-Dossoki +1 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Quantitative indication of the process of forming a complex comes from the evaluation of the stability constants, which characterize the equilibria corresponding to the successive addition of ligands.
Brij Bhushan Tewari
doaj +1 more source
The evolutionary stability of constant consistent conjectures [PDF]
In the general context of smooth two-player games, this paper shows that there is a close connection between (constant) consistent conjectures in a given game and the evolutionary stability of these conjectures. Evolutionarily stable conjectures are consistent and consistent conjectures are the only interior candidates to be evolutionarily stable ...
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An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The stability of fundamental constants
The tests of the constancy of fundamental constants are tests of the local position invariance and thus of the equivalence principle, at the heart of general relativity. After summarising the links between fundamental constants, gravity, cosmology and metrology, a brief overview of the observational and experimental constraints on their variation is ...
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