Results 61 to 70 of about 644,626 (265)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Determination of the Stability Constant of Vanadium (V) with Alaine [PDF]
Formation equilibria of dioxy vanadium (V) complex with alanine in acidic media ...
Saeed Abedini Khorrami +3 more
doaj
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Stability of helicoidal surfaces with constant mean curvature
Motivated by an experimental result on the shape of liquid water supported by a small stainless helical wire, we find a class of stable helicoidal convex surfaces with constant mean curvature whose boundary consists of a single helix and two short arcs.
Yuta Hatakeyama, Miyuki Koiso
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Effect of Mg and Ca on the Stability of the MRI Contrast Agent Gd–DTPA in Seawater
Gadolinium diethylenetriaminepentaacetic acid (Gd–DTPA) is widely applied as a contrast enhancer in medical MRI. As Gd–DTPA is only minimally captured in wastewater treatment plants (WTPs) or degraded by UV light and other oxidative processes ...
Johan Schijf, Isabel J. Christy
doaj +1 more source
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Developmental stability in constant and fluctuating temperatures
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire +1 more source

