Results 131 to 140 of about 794,434 (267)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Primary fixation stability evaluation of pre-bent titanium miniplate configurations in mandibular reconstruction. [PDF]

Front Bioeng Biotechnol
Ruf P, Cebeci Ö, Orassi V, Steffen C, Duda GN, Heiland M, Checa S, Rendenbach C.   +7 more
europepmc   +1 more source

Nonlinear Strength Reduction Method of Rock Mass in Slope Stability Evaluation. [PDF]

Materials (Basel), 2023
Chen Y, Chen Y, Lin H, Hu H.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Volumetric absorptive microsampling for lumateperone analysis: method validation and stability evaluation. [PDF]

Anal Bioanal Chem
Milandri E, Di Lecce R, Iattoni CP, Armirotti A, Vovk T, Mandrioli R, Protti M, Mercolini L.   +7 more
europepmc   +1 more source

Physics-based and data-driven modeling for basal stability evaluation of braced excavations in natural clays. [PDF]

Heliyon, 2023
Lai VQ, Kounlavong K, Keawsawasvong S, Wipulanusat W, Jamsawang P.   +4 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Laccase Immobilization on Carbon-Based Materials Derived from Spent Brewery Grains: Optimization and Stability Evaluation. [PDF]

Molecules
Almeida Â, Pereira M, Peleja A, Rocha HF, Otero M, Pereira G, Calisto V.   +6 more
europepmc   +1 more source

Cluster-based stability evaluation in time series data sets. [PDF]

Appl Intell (Dordr), 2022
Klassen G, Tatusch M, Conrad S.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source