Results 41 to 50 of about 145,542 (292)
Update of Natural Compounds in Transthyretin Amyloidosis, Years 2020–2025
CrystalsTransthyretin amyloidosis (ATTR) is a disease caused by the deposition of transthyretin-derived fibrils in the body. Despite extensive research conducted over the years, there are currently only four drugs available in clinical use to treat this ...
Carlo Marotta +2 more
doaj +1 more source
Affine hypersurfaces admitting a pointwise symmetry
, 2005 An affine hypersurface is said to admit a pointwise symmetry, if there exists a subgroup of the automorphism group of the tangent space, which preserves (pointwise) the affine metric h, the difference tensor K and the affine shape operator S.
Lu, Ying, Scharlach, Christine
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Veterinary SciencesPeste des Petits Ruminants (PPR) disease is widely distributed in Africa. Live attenuated PPR vaccines are produced using approved Nigeria 75/1 and Sungri/96 strains by the World Organisation of Animal Health (WOAH) to control the disease.
Amadou Diallo +12 more
doaj +1 more source
Gels, 2021 The modern brewing industry generates high amounts of solid wastes containing biopolymers—proteins and polysaccharides—with interesting technological and functional properties. The novelty of this study was to use raw by-product from the brewing industry
Adrián López-García +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Pharmaceutics, 2021 Luteolin is a natural drug used as an antioxidant and anti-inflammatory, but unfortunately, it possesses low water solubility, which hinders its delivery via the skin.
Mohammed Elmowafy +6 more
doaj +1 more source
On the one-endedness of graphs of groups [PDF]
, 2015 We give a technical result that implies a straightforward necessary and sufficient conditions for a graph of groups with virtually cyclic edge groups to be one ended.
Touikan, Nicholas
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Stabilizers, Measures and IP-sets
, 2020 The purpose of this simple note is to provide elementary model-theoretic proofs to some existing results on sumset phenomena and IP sets, motivated by Hrushovski's work on the stabilizer ...
Martin-Pizarro, Amador, Palacín, Daniel
core