Results 171 to 180 of about 26,038 (246)

A sensitive liquid chromatography-tandem mass spectrometry analytical method of steroid hormones in small blubber samples from four whale species. [PDF]

Conserv Physiol
Dulgheriu D, Andvik C, Jourdain E, Borgå K, Ruus A, Haug T, Karoliussen R, Lyche JL, Horsberg TE.   +8 more
europepmc   +1 more source

The R203W substitution drives PACS‐1 syndrome by disrupting intramolecular regulation

The FEBS Journal, EarlyView.
The middle region (MR) of PACS‐1 controls engagement with specific partner proteins. This manuscript presents the structure of the Furin binding region (FBR) and how interactions with partners are regulated through the interplay between a basic patch in the FBR and an acidic cluster in the MR.
Troy C. Krzysiak, In‐Ja L. Byeon, Ryan Ponticelli, Mary E. Lucas, Lariah Thompson, Christopher DeHaven, Gary Thomas, Angela M. Gronenborn   +7 more
wiley   +1 more source

KRAS Signaling Inhibition Induces a Targetable Metabolic Dependency on Lipophagy-Dependent Fatty Acid Oxidation in Pancreatic Cancer. [PDF]

Cancer Res
Thakur R, Wang D, Hu T, He C, Zhao J, Suresh V, Rajacharya GH, Pradhan AK, Chumak V, Valenzuela CA, Kushwaha AD, Labreck DA, Oh TG, Fung KM, Zhao D, Takebe N, Ulahannan SV, Shukla SK, Bryant KL, Der CJ, Mehla K, Singh PK.   +21 more
europepmc   +1 more source

Development of CCMb: A Low‐Mg Calcite Reference Material for In Situ Measurement of δ18O, δ13C and Selected Trace Elements

Geostandards and Geoanalytical Research, EarlyView.
Key Points Low‐Mg calcite RM developed for in situ microanalysis applications in palaeoclimatology (δ18O, δ13C; Mg, Sr m/m). New data for calcite CRM IAEA‐603 (δ18O, δ13C by SIMS and GS‐IRMS; Mg m/m). No detectable IMF effect of Mg on SIMS δ18O determinations for mass fractions < 3650 μg g‐1.
Andreas T. Hertwig, Maciej G. Śliwiński, Irene Cantarero, Richard A. Stern, Carles Fàbrega, Jakub T. Śliwiński, Thomas Ludwig, František Majs, William Nachlas, John H. Fournelle, Xavier Llovet, Rachelle B. Turnier, David Parcerisa, Anna Travé   +13 more
wiley   +1 more source

Transitioning from Laboratory-Developed Tests to a Single Commercial Reagent Kit in a National Newborn Screening Program: Impact on Analytical Performance and Harmonization. [PDF]

Int J Neonatal Screen
Carling RS, Barclay ZJ, Ward SC, Appleton M, Barski R, Benn H, Chambers K, Coakley P, Kemp H, Crabbe N, Dowden S, Greenfield T, Hogg SL, Hussein S, Marr R, Parkes O, Powell D, Ramgoolam T, Ssali J, Taj N, Wright K, Wu THY, Bonham JR.   +22 more
europepmc   +1 more source

Non‐native pink salmon Oncorhynchus gorbuscha carcasses benefit native benthic macroinvertebrates

Journal of Fish Biology, EarlyView.
Abstract The invasion of the North Atlantic by pink salmon Oncorhynchus gorbuscha has raised concerns regarding their impact on coastal rivers. Although the influence of marine‐derived nutrients from returning adult O. gorbuscha on rivers in their native range has received much attention, the ecological consequences of invasive O.
Hui Wei, Gordon H. Copp, Rasmus B. Lauridsen, Tea Bašić, Phil I. Davison, John F. Murphy, James L. Pretty, Michał E. Skóra, Gabriela Zemelka, John Iwan Jones   +9 more
wiley   +1 more source

Development of an LC-MS/MS assay to analyze a lipid-conjugated siRNA by solid phase extraction (SPE) in mouse plasma and tissue using a stable isotope labeled internal standard (SILIS). [PDF]

Bioanalysis
Sanford EJ, Chen J, Tran J, Korboukh I, Zhang G.   +4 more
europepmc   +1 more source

Chain‐Length Regulation by WzzE Is Necessary for, but Genetically Separable From, Cyclic Enterobacterial Common Antigen Synthesis

Molecular Microbiology, EarlyView.
Here, we demonstrate that polysaccharide chain length regulation plays a distinct role in enabling formation of a cyclic molecule important for the bacterial cell surface. However, this function is necessary, but not sufficient for the cyclic molecule's biosynthesis.
Joseph F. Carr, Yohannes H. Rezenom, Jennifer S. Rudolf, Daniel J. Warzecha, Angela M. Mitchell   +4 more
wiley   +1 more source

Quantitation of Vitamin B6 Vitamers and Glycosides in German Alcohol-Free and Full-Strength Beer by a Stable Isotope Dilution LC-MS/MS Method. [PDF]

J Agric Food Chem
Jahner S, Geilich E, Hagenauer C, Rychlik M.   +3 more
europepmc   +1 more source