Results 181 to 190 of about 2,787,968 (277)

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

Immunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan, David E. Phelan, Xiaofei Yin, Lorraine Brennan, Martina Wallace, Eoin P. Cummins   +5 more
wiley   +1 more source

Characterization of key off-flavor compounds in soybean and their dynamic changes during progressive processing. [PDF]

Front Nutr
Zhou J, Huang D, Xu S, Li J, Liu J, Li Y, Zhang W.   +6 more
europepmc   +1 more source

Marine migration influences mercury accumulation in anadromous Arctic char (Salvelinus alpinus)

Journal of Fish Biology, EarlyView.
Abstract Mercury (Hg) is a globally distributed toxic metal present in northern natural environments that biomagnifies in food webs and bioaccumulates in apex predator fish, such as Arctic char (Salvelinus alpinus)—an iteroparous species with a circumpolar distribution. Arctic char exhibit a variety of life history types, with the migrating, anadromous
Isabel R. Hilgendag, Michael Power, Mehdi M. Aqdam, Christopher W. Lewis, Zoya Martin, Ashley D. Ehrman, Heidi K. Swanson   +6 more
wiley   +1 more source

Isotope Dilution NanoLC-MS/MS Quantitation of Methylglyoxal DNA-Protein Cross-Links: Formation and Repair in Human Cells. [PDF]

Anal Chem
Omondi RO, Barnes EM, Gurajala KC, Fisette G, Chaudray IA, Erber L.   +5 more
europepmc   +1 more source

Body Composition, Physical Activity and Energy Requirements Estimated Using Two Isotopic Methods in Old and Adult Beagle Dogs

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Energy requirements (ER) are known to decline as dogs age into the senior stage. However, the implications of body composition and physical activity (PA) on this parameter remain poorly investigated. The aim of this study was to evaluate ER, body composition, water turnover rate (WTR), and voluntary PA by triaxial accelerometers in adults (5.2 
Ariel de Castro, Letícia Graziele Pacheco, Camila Goloni, Vladimir Eliodoro Costa, Aulus Cavalieri Carciofi   +4 more
wiley   +1 more source

Tissue Depletion in Dairy Cattle Following Administration of Label or Extralabel Doses of Penicillin G Using Two Different Formulations

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Penicillin G has been one of the main violative residues detected at slaughter for 25+ years. Accordingly, a residue depletion study was initiated to determine possible reasons, using a two‐phase approach. Phase 1 involved a 2 × 2 matrix using either the 4‐ or 14‐day withdrawal period product at label dosage (1×) or three times the label dose (
Michael J. Myers, O. Alberto Chiesa, Linge Li, Karyn D. Howard, Rachael Cohen, Raoul Gonzales   +5 more
wiley   +1 more source

Application of 2D-Chromatography System for the Determination of Cosmetic Peptides in Skin Homogenates. [PDF]

J Mass Spectrom
Errante F, Pallecchi M, Menicatti M, Giovannelli L, Rovero P, Bartolucci G.   +5 more
europepmc   +1 more source

A Microkrystite from the Australasian Tektite/Microtektite Strewn Field

Meteoritics &Planetary Science, EarlyView.
Abstract Microkrystites are glassy impact spherules. They contain primary crystallites carrying information on the physical and chemical conditions prevailing during vaporization, melting, and ejection in large impact cratering events. We report on the geochemistry and mineralogy down to nanometer scale of the first microkrystite (ODP1144A,14) from the
Matteo Del Rio, Luigi Folco, Matteo Masotta, Ana Černok, Enrico Mugnaioli   +4 more
wiley   +1 more source

Simultaneous quantification of cytidine, methylcytidine, and hydroxymethylcytidine by isotope-dilution LC-MS/MS with application to mouse liver samples. [PDF]

J Chromatogr A
Mishra P, Ma J, Xie H, Li F, Tsai RYL, Liang D.   +5 more
europepmc   +1 more source

Apoplast multi‐omics profiling during fungal infection uncovers new players of basal and early induced immunity in Arabidopsis thaliana

New Phytologist, EarlyView.
Important processes taking place in the apoplast during plant–pathogen interaction identified by multi‐omics profiling of the apoplastic fluid. Summary The extracellular space in plant tissues, known as the apoplast, remains one of the least characterized cellular compartments.
Antoine Davière, Sylvie Jolivet, Annie Auger, Gilles Clement, Stephanie Boutet, Jean Chrisologue Totozafy, Thierry Balliau, Mélisande Blein‐Nicolas, Justine Rouffet, Marie‐Christine Soulié, Mathilde Fagard   +10 more
wiley   +1 more source