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Stable isotope dilution assays as tools for assessing folate bioavailability
2012Folates play a crucial role as coenzymes in the metabolism of one-carbon groups and folate deficiency is considered to increase the risk of neural tube defects.To evaluate folate bioavailability, two short-term designs were applied.In the first investigation, a large-scale human study with application of model foods revealed a low folate ...
Rychlik, Michael +7 more
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Journal of Agricultural and Food Chemistry, 2000
A stable isotope dilution assay for quantification of pantothenic acid in food and blood plasma uses a 4-fold labeled isotopomer of the vitamin as an internal standard. Pantothenic acid and its labeled analogue were detected as trimethylsilyl derivatives by gas chromatography-mass spectrometry, showing a minimized spectral overlap.
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A stable isotope dilution assay for quantification of pantothenic acid in food and blood plasma uses a 4-fold labeled isotopomer of the vitamin as an internal standard. Pantothenic acid and its labeled analogue were detected as trimethylsilyl derivatives by gas chromatography-mass spectrometry, showing a minimized spectral overlap.
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Determination of Vitispirane in Wines by Stable Isotope Dilution Assay
American Journal of Enology and Viticulture, 2006Nigel J. Eggers +2 more
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A stable isotope dilution mass spectrometric assay for the major urinary metabolite of PGD2.
Advances in prostaglandin, thromboxane, and leukotriene research, 19911. A sensitive and specific negative ion chemical ionization mass spectrometric assay for the major urinary metabolite of PGD2 has been developed employing a chemically synthesized [18(0)4]-labelled internal standard. 2. The finding that increased urinary excretion of this metabolite occurs in a number of clinical situations suggests that the assay may
J D, Morrow +6 more
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Quantitation of Trichothecene Mycotoxins by Stable Isotope Dilution Assays
2008Michael Rychlik, Stefan Asam
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