Results 221 to 230 of about 19,434,090 (311)

Targeting Cannabinoid 1 Receptor in Macrophages Alleviates Psoriatic Skin Inflammation Through the AUF1–NLRP3 Axis

Advanced Science, EarlyView.
Macrophage CB1R emerges as a key driver of psoriatic inflammation by suppressing AUF1‐mediated post‐transcriptional control of NLRP3. CB1R inhibition restores AUF1‐dependent NLRP3 mRNA decay, restrains inflammasome activation, and alleviates psoriasis‐like inflammation.
Hongseo Choi, Sukyoung Han, Jinho Kim, Ji Hye Han, Eunsu Kim, Yeonjeong Heo, Minju Lee, Jooyoung Lee, Heerim You, Soyoun Lee, Su‐Hee Han, Ilrok Yoon, Sung Anjeon, Hyerim Kang, Seungyeon Ryu, Hyun‐Ji Park, Eunha Kim, Chul Hwan Bang, Ji Hyun Lee, Josephine M. Egan, Jung‐Woong Kim, Eun Kyung Lee, Wook Kim   +22 more
wiley   +1 more source

Exploring the role of Human Factors and Ergonomics in supporting safe insulin dispensing in community pharmacy: a pilot webinar-based training intervention. [PDF]

BMJ Open Qual
Carrington A, Vosper H, Bowie P.
europepmc   +1 more source

Pre‐Refinement Prediction of Dopant Site Occupancy in M‐Type Hexaferrites via Hierarchical and Uncertainty‐Aware Machine‐Learning

Advanced Science, EarlyView.
Refined data are extracted from CIF files to construct a hierarchical machine‐learning framework integrating sublattice classification, Fe‐site occupancy prediction, and reliability assessment. External validation yields 96% accuracy for sublattice classification and a macro mean absolute error of 0.0584 for Fe‐site prediction.
Dan Liu, Jianyu Ren, Ruoshui Liu, Yinong Yin, Jianfeng Xi, Xin Ming, Jiazheng Hao, Tongyun Zhao, Fengxia Hu, Baogen Shen   +9 more
wiley   +1 more source

Beyond novice-to-expert progression: a context-enabled continuing professional development framework derived from nursing practice in resource-constrained South African hospitals. [PDF]

Front Med (Lausanne)
Nyelisani M, Makhado L.
europepmc   +1 more source

A Multi‐Structural Radiomic Digital Phenotyping Framework for Deciphering Preclinical Evolution of Degenerative Meniscal Tears

Advanced Science, EarlyView.
Subclinical matrix disruption precedes degenerative meniscal tears across the knee joint. A spatial compartmental radiomics model utilizing 3D‐DESS MRI captures early osteochondral destabilization, accurately predicting incident tears up to four years pre‐collapse. Feature attributions uncover coordinated chondral and osseous alterations, advancing non‐
Shengfa Li, Hao Liu, Yanbin Zhu, Hang Zhang, Qifeng Tao, Wenbo Zhao, Xin Miao, Shanshan Yang, Tianyu Chen, David Hunter, Changhai Ding, Ting Wang, Juan Wang, Wei Chen   +13 more
wiley   +1 more source

Engaging Service Users in Co-Designing a Nurse-Led Weight Talk Tool for Low- and Medium-Secure Mental Health Inpatient Settings: A Participatory Intervention Development Study. [PDF]

Int J Ment Health Nurs
Mak NKN, Dibb B, Stokes N, Barley EEA, Zasada M.   +4 more
europepmc   +1 more source

Next Generation Antimicrobial Coatings for High Touch Surfaces: Application, Benefits, Risks, Environmental Impacts and Sustainability Aspects

Advanced Science, EarlyView.
Antimicrobial coatings for high touch surfaces promise infection control but are too often validated only in the lab. This review shows that active‐agent release governs both human toxicity and environmental impact and argues that durability and real‐world performance must be primary design criteria, placing a safe‐and‐sustainable‐by‐design framework ...
Nurshen Mutlu, Peter Askew, Alexander J. Cunliffe, Damjana Drobne, Stefan Fischer, Gillian Iredale, Pascal Kock, Veno Kononenko, Susanne Kurz, Patrick Lichtner, Abby Marchant, Philipp Meier, James Redfern, Giacomo Reina, Simone Schulte, Juliane Spohn, Merve Tunali, Peter Wick, Nihal Engin Vrana, Bernd Nowack   +19 more
wiley   +1 more source

Development of a village health worker care model to reduce cardiovascular risk in areas of armed conflict: Qualitative results from a participatory planning process in Myanmar. [PDF]

PLOS Glob Public Health
Htoo E, Parmar P, Richards A, Russell T, Lee C, Law SSK, Myint SK, Aung ZYP, Traill T.   +8 more
europepmc   +1 more source

The Interplay Between Molybdopterin Synthase and Metal Metabolism Contributes to Pathogenicity in Acinetobacter baumannii

Advanced Science, EarlyView.
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao, Wenbo He, Zhenlin Ouyang, Ruochen Wang, Jiaxin Zhang, Xin Liu, Yiting Jing, Qinyue Yu, Xiaoyu He, Qian Qin, Litao Guo, Peter M. Hwang, Fang Zheng, Yurong Wen   +13 more
wiley   +1 more source

The Unseen Side of Nursing Leadership: Conceptualizing Leadership Blind Spots in Healthcare Settings. [PDF]

Nurs Open
Abou Hashish EA.
europepmc   +1 more source