Results 41 to 50 of about 19,434,090 (311)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Collaborative Semantic Annotation Tooling (CoAT) to Improve Efficiency and Plug-and-Play Semantic Interoperability in the Secondary Use of Medical Data: Concept, Implementation, and First Cross-Institutional Experiences

Applied Sciences
The cross-institutional secondary use of medical data benefits from structured semantic annotation, which ideally enables the matching and merging of semantically related data items from different sources and sites.
Thomas Wiktorin, Daniel Grigutsch, Felix Erdfelder, Andrew J. Heidel, Frank Bloos, Danny Ammon, Matthias Löbe, Sven Zenker   +7 more
doaj   +1 more source

Video for peer feedback and reflection: embedding mainstream engagement into learning and teaching practice [PDF]

Research in Learning Technology, 2012
This paper discusses the benefits and challenges of video as a tool for supporting and enhancing peer feedback and reflection. The analysis draws on key arguments from relevant literature in combination with the author's own experiences of ...
Lindsay Jordan
doaj   +1 more source

Efecto de un curso sobre medicina basada en la evidencia: análisis exploratorio

MedUNAB, 2023
RESUMEN Introducción. Tomar decisiones clínicas basadas en la mejor evidencia disponible es una buena práctica que favorece los resultados en salud.
Lorena Mesa-Melgarejo, Carol Zarate-Ardila   +1 more
doaj   +1 more source

Evaluation Report: An Evaluation of UNDP Participation in the Execution of Bank-funded Operations [PDF]

, 2000
This report (RE-240) by the Evaluation Office presents the findings of an evaluation of the cooperation between the Bank and the United Nations Development Programme (UNDP) in the execution of Bank-funded programs.
Inter-American Development Bank
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Integrated transcriptomic and metabolomic analysis of resistant and susceptible Nicotiana tabacum L. reveals the mechanisms of selenium-induced disease resistance to Phytophthora nicotianae

Frontiers in Plant Science
Tobacco black shank, a destructive soil-borne disease caused by Phytophthora nicotianae, severely impacts tobacco production. Selenium (Se) is a beneficial trace element known to enhance plant stress resistance.
Kai Zhang, Xiaohan Ma, Jiaying Li, Fazhan Wang, Wenchao Wang, Jiashu Tian, Huanyu Teng, Yingjie Liu, Jiayang Xu, Huiwei Niu, Wei Jia   +10 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Prediction of Structural Response for HSSCC Deep Beams Implementing a Machine Learning Approach

International Journal of Coastal and Offshore Engineering, 2018
High Strength Concrete (HSC) is a complex type of concrete, that meets the combination of performance and uniformity at the same time. This paper demonstrates the use of artificial neural networks (ANN) to predict the deflection of high strength ...
Mohammad Mohammadhassani, Mahdi Zarrini, Ehsan Noroozinejad Farsangi, Neda Khadem Gerayli   +3 more
doaj