Results 81 to 90 of about 355,639 (301)
Effect of probenecid on SR101-labeling.
, 2012 A: Overlay of astroglial EGFP-fluorescence and SR101-fluorescence in the VLM after staining in CTRL conditions. B: Overlay of astroglial EGFP- and SR101-fluorescence after staining with Probenecid (Prob, 1 mM). C,D: Statistical comparison shows no change
Christian Schnell (117226) +2 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 1991 We have developed a new double labeling method for electron microscopy to characterize selectively two physiologically identified neurons on the same preparation.
A Buisson, F Nagy, L Nonnotte, M Moulins
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The application of special staining in neuropathological diagnosis
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Special staining plays an important role in the clinical neuropathological diagnosis. Some special staining is used to distinguish the specific structure of neuron, such as Nissl staining for Nissl body.
Yong-juan FU, Yue-shan PIAO, De-hong LU
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Capillary blood as an alternative specimen for enumeration of percentages of lymphocyte subsets
BMC Research Notes, 2019 Objective Capillary blood has been increasingly used in point-of-care setting for clinical monitoring in immunology and infectious diseases. We explored whether percentages of lymphocyte subsets (T-cells; CD3+, helper T-cells; CD4+, cytotoxic T-cells ...
Supanart Srisala +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The application of different staining methods in the morphological observation of non-decalcified bone tissue sections containing implants [PDF]
精准医学杂志Objective To investigate the application and advantages of different staining methods in the morphological observation of non-decalcified bone tissue sections containing implants.
XU Qian, ZHANG Fan, ZHANG Liguo
doaj +1 more source
Understanding the Pathogenesis of Neuroinflammation using Magnetic Resonance Imaging [PDF]
, 2011 A non-invasive view of the brain with the aid of magnetic resonance imaging (MRI) is invaluable for studying pathological processes during autoimmune encephalomyelitis.
Waiczies, Sonia +3 more
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