Results 81 to 90 of about 546,652 (251)

Abnormal motoneuron migration, differentiation, and axon outgrowth in spinal muscular atrophy [PDF]

, 2008
The role of heterotopic (migratory) motoneurons (HMN) in the pathogenesis of spinal muscular atrophy (SMA) is still controversial. We examined the occurrence and amount of HMN in spinal cord tissue from eight children with SMA (six with SMA-I and two ...
Barišić, Nina, Hof, Patrick R., Islam, Atiqul, Jovanov Milošević, Nataša, Krušlin, Božo, Lucassen, Paul J., Mladinov, Mihovil, Pajtak, Alen, Sertić, Jadranka, Šešo Šimić, Đurđica, Šimić, Goran   +10 more
core   +1 more source

Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons.

Brain Research, 2005
The causes and effects of neuronal degeneration are of major interest to a wide variety of neuroscientists. Paralleling this growing interest is an increasing number of methods applicable to the detection of neuronal degeneration.
L. Schmued, Chris Stowers, A. Scallet, Lulu Xu   +3 more
semanticscholar   +1 more source

Enhanced Histochemical Detection of Iron in Paraffin Sections of Mouse Central Nervous System Tissue

ASN Neuro, 2016
Histochemical methods of detecting iron in the rodent brain result mainly in the labeling of oligodendrocytes, but as all cells utilize iron, this observation suggests that much of the iron in the central nervous system goes undetected.
Scott A. Sands, Regis Leung-Toung, Yingsheng Wang, John Connelly, Steven M. LeVine   +4 more
doaj   +1 more source

Capillary blood as an alternative specimen for enumeration of percentages of lymphocyte subsets

BMC Research Notes, 2019
Objective Capillary blood has been increasingly used in point-of-care setting for clinical monitoring in immunology and infectious diseases. We explored whether percentages of lymphocyte subsets (T-cells; CD3+, helper T-cells; CD4+, cytotoxic T-cells ...
Supanart Srisala, Nutkridta Pongsakul, Thiantip Sahakijpicharn, Suradej Hongeng, Somchai Chutipongtanate, Nopporn Apiwattanakul   +5 more
doaj   +1 more source

Increased apoptosis of immunoreactive host cells and augmented donor leukocyte chimerism, not sustained inhibition of B7 molecule expression are associated with prolonged cardiac allograft survival in mice preconditioned with immature donor dendritic cells plus anti-CD40L mAb [PDF]

, 1999
Background. We previously reported the association among donor leukocyte chimerism, apoptosis of presumedly IL-2-deficient graft-infiltrating host cells, and the spontaneous donor-specific tolerance induced by liver but not heart allografts in mice ...
Angus W. Thomson, Aust, Bishop, Bishop, Buhlmann, Cohn, Cuiping Zhong, Dai, Demetris, Durie, Effros, Ehl, Fu, Hancock, Inaba, Janeway, Jenkins, John J. Fung, Kneitz, Konieczny, Larsen, Larsen, Lenschow, Lina Lu, Lu, Lu, Lu, Lu, Lu, Markees, Matzinger, Meyer, Morecki, Murase, Murase, Murase, Niimi, Ohashi, Ohashi, Parker, Picker, Qian, Qian, Rafaeli, Rastellini, Sayegh, Schwartz, Shiguang Qian, Starzl, Starzl, Starzl, Starzl, Sun, Taniguchi, Thomas E. Starzl, Thomson, Thomson, Van Parijs, Wei Li, Wekerle, Willerford, Zinkernagel, Zinkernagel, Zinkernagel   +63 more
core   +1 more source

Palladium-based Mass-Tag Cell Barcoding with a Doublet-Filtering Scheme and Single Cell Deconvolution Algorithm

Nature Protocols, 2015
Mass-tag cell barcoding (MCB) labels individual cell samples with unique combinatorial barcodes, after which they are pooled for processing and measurement as a single multiplexed sample.
E. Zunder, R. Finck, G. Behbehani, E. Amir, Smita Krishnaswamy, Veronica D. Gonzalez, C. Lorang, Zach Bjornson, M. Spitzer, B. Bodenmiller, W. Fantl, D. Pe’er, G. Nolan   +12 more
semanticscholar   +1 more source

Chondrosarcoma evaluation using hematein-based x-ray staining and high-resolution 3D micro-CT: a feasibility study

European Radiology Experimental
Background Chondrosarcomas are rare malignant bone tumors diagnosed by analyzing radiological images and histology of tissue biopsies and evaluating features such as matrix calcification, cortical destruction, trabecular penetration, and tumor cell ...
Alexandra S. Gersing, Melanie A. Kimm, Christine Bollwein, Patrick Ilg, Carolin Mogler, Felix G. Gassert, Georg C. Feuerriegel, Carolin Knebel, Klaus Woertler, Daniela Pfeiffer, Madleen Busse, Franz Pfeiffer   +11 more
doaj   +1 more source

Loss of neurons from laminas I-III of the spinal dorsal horn is not required for development of tactile allodynia in the spared nerve injury model of neuropathic pain [PDF]

, 2005
It has been proposed that death of inhibitory interneurons in the dorsal horn contributes to the neuropathic pain that follows partial nerve injury. In this study, we have used two approaches to test whether there is neuronal death in the dorsal horn in ...
Arham, A.Z., Hughes, D.I., Polgar, Erika, Todd, A.J.   +3 more
core   +2 more sources

Virtual staining of label-free tissue in imaging mass spectrometry

Science Advances
Imaging mass spectrometry (IMS) enables untargeted, highly multiplexed mapping of molecular species in biological tissue with unparalleled chemical specificity and sensitivity. However, most IMS platforms lack microscopy-level spatial resolution and cellular morphological contrast, necessitating subsequent histochemical staining, microscopic imaging ...
Yijie Zhang, Luzhe Huang, Nir Pillar, Yuzhu Li, Yuhang Li, Lukasz G. Migas, Raf Van de Plas, Jeffrey M. Spraggins, Aydogan Ozcan   +8 more
openaire   +4 more sources

Novel components of the Toxoplasma inner membrane complex revealed by BioID. [PDF]

, 2015
UNLABELLED:The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to a supporting cytoskeletal network. The IMC plays important roles in
Bell, Hannah N, Bentolila, Laurent A, Bradley, Peter J, Chen, Allan L, Huang, Amy S, Kim, Elliot W, Moon, Andy S, Rashoff, Andrew Q, Toh, Justin Y, Van, Christina, Vashisht, Ajay A, Wohlschlegel, James A   +11 more
core   +3 more sources