Results 81 to 90 of about 359,491 (304)

Chondrosarcoma evaluation using hematein-based x-ray staining and high-resolution 3D micro-CT: a feasibility study

European Radiology Experimental
Background Chondrosarcomas are rare malignant bone tumors diagnosed by analyzing radiological images and histology of tissue biopsies and evaluating features such as matrix calcification, cortical destruction, trabecular penetration, and tumor cell ...
Alexandra S. Gersing, Melanie A. Kimm, Christine Bollwein, Patrick Ilg, Carolin Mogler, Felix G. Gassert, Georg C. Feuerriegel, Carolin Knebel, Klaus Woertler, Daniela Pfeiffer, Madleen Busse, Franz Pfeiffer   +11 more
doaj   +1 more source

Label-free color staining of quantitative phase images

Optics and Lasers in Engineering, 2020
Abstract Phase contrast microscopy enables the label-free visualization of “phase-only” objects such as unstained biological cells. This approach produces a contrast in image intensity that relates qualitatively to the phase delay introduced by the specimen.
Xin Fan, John J. Healy, Kevin O’Dwyer, Bryan M. Hennelly   +3 more
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Hoechst 33342 staining.

, 2013
Fluorescence microscope images on Hoechst 33342 staining from (A) MCF7 cells and (B) CNE2 cells treated with brown kidney bean lectin for 24 and 48 hours respectively.
Wenliang Pan (319428), Tzi Bun Ng (287770), Evandro Fei Fang (308715), Jack Ho Wong (308722), Yau Sang Chan (287769)   +4 more
core   +1 more source

Enhanced Histochemical Detection of Iron in Paraffin Sections of Mouse Central Nervous System Tissue

ASN Neuro, 2016
Histochemical methods of detecting iron in the rodent brain result mainly in the labeling of oligodendrocytes, but as all cells utilize iron, this observation suggests that much of the iron in the central nervous system goes undetected.
Scott A. Sands, Regis Leung-Toung, Yingsheng Wang, John Connelly, Steven M. LeVine   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Representative immunohistochemical staining for ERCC1 in esophageal squamous cell carcinoma.

, 2014
Such staining was used for classification of nuclear staining intensity and assignment of a corresponding H-score used in further analyses in the study.
Ya-Yun Chen (626516), Yi-Feng Chen (368028), Zhi-Shan Zhang (2624494), Pei-Ling Xin (626514), Wan-Hua Chen (626513), Qun-Xiong Pan (626515), Chao-Yang Zhang (626517), Cong-Ren Wang (450270), Wen-Jie Cai (626518)   +8 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Combination of horseradish peroxidase and lucifer yellow staining for selective labeling of neurons at the electron microscopic level.

, 1991
We have developed a new double labeling method for electron microscopy to characterize selectively two physiologically identified neurons on the same preparation.
A Buisson, F Nagy, L Nonnotte, M Moulins
core   +1 more source

Linking structure and function of the asialoglycoprotein receptor H1-CRD using site-directed mutagenesis and isotope labeling [PDF]

, 2007
The asialoglycoprotein receptor (ASGP-R) is a C-type lectin, abundantly expressed on hepatocytes. It mediates the clearance of desialylated glycoproteins carrying terminal galactose (Gal) or N-acetyl-galactosamine (GalNAc) residues through endocytosis ...
Johansson, Anna Karin
core   +1 more source