Results 91 to 100 of about 563,924 (339)

The structure of the Onsala 1 star forming region [PDF]

Astronomy & Astrophysics, 2004
We present new high-sensitivity high-resolution mm-wave observations of the Onsala 1 ultra-compact HII region that bring to light the internal structure of this massive star forming cloud. The 1.2 mm continuum map obtained with the IRAM 30-m radiotelescope (~11" resolution) shows a centrally peaked condensation of 1' size (~0.5 pc at the assumed ...
M. S. N. Kumar, Rafael Bachiller, Mario Tafalla   +2 more
openaire   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Spectroscopic studies of star forming regions [PDF]

Commun. Konkoly Obs. Hung. Acad. Sci., No. 104, (2006), pp. 121-132 (Detre Centennial Conference), 2006
This paper reviews the results of studies of star forming regions, carried out at the Konkoly Observatory in the last two decades. The studies involved distance determination of star-forming dark clouds, search for candidate pre-main sequence stars, and determination of the masses and ages of the candidates by spectroscopic follow-up observations.
arxiv  

Fragmentation of a high-mass star-forming core [PDF]

, 2004
At the earliest evolutionary stages, massive star-forming regions are deeply embedded within their natal cores and not observable at optical and near-infrared wavelengths. Interferometric high-spatial resolution mm dust continuum observations of one very young high-mass star-forming region disentangle its cluster-like nature already at the very ...
arxiv   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

ALMA-IMF. XIV. Free–Free Templates Derived from H41α and Ionized Gas Content in 15 Massive Protoclusters

The Astrophysical Journal Supplement Series
We use the H41 α recombination line to create templates of the millimeter free–free emission in the ALMA-IMF continuum maps, which allows us to separate it from dust emission.
Roberto Galván-Madrid, Daniel J. Díaz-González, Frédérique Motte, Adam Ginsburg, Nichol Cunningham, Karl M. Menten, Mélanie Armante, Mélisse Bonfand, Jonathan Braine, Timea Csengeri, Pierre Dell’Ova, Fabien Louvet, Thomas Nony, Rudy Rivera-Soto, Patricio Sanhueza, Amelia M. Stutz, Friedrich Wyrowski, Rodrigo H. Álvarez-Gutiérrez, Tapas Baug, Sylvain Bontemps, Leonardo Bronfman, Manuel Fernández-López, Antoine Gusdorf, Atanu Koley, Hong-Li Liu, Javiera Salinas, Allison P. M. Towner, Anthony P. Whitworth   +27 more
doaj   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

The Monoceros R2 Molecular Cloud [PDF]

arXiv, 2008
The Monoceros R2 region was first recognized as a chain of reflection nebulae illuminated by A- and B-type stars. These nebulae are associated with a giant molecular cloud that is one of the closest massive star forming regions to the Sun. This chapter reviews the properties of the Mon R2 region, including the namesake reflection nebulae, the large ...
arxiv  

On the mass segregation of cores and stars [PDF]

, 2019
Observations of pre-/proto-stellar cores in young star-forming regions show them to be mass segregated, i.e. the most massive cores are centrally concentrated, whereas pre-main sequence stars in the same star-forming regions (and older regions) are not.
arxiv   +1 more source