Results 101 to 110 of about 318,054 (345)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Tracking Star-forming Cores as Mass Reservoirs in Clustered and Isolated Regions Using Numerical Passive Tracer Particles

open access: yesThe Astrophysical Journal
Understanding the physical properties of star-forming cores as mass reservoirs for protostars and the impact of turbulence is crucial in star formation studies.
Shingo Nozaki   +3 more
doaj   +1 more source

An Ultraviolet Study of Star-Forming Regions in M31

open access: yes, 2009
We present a comprehensive study of star-forming (SF) regions in the nearest large spiral galaxy M31. We use GALEX far-UV (1344-1786 \AA, FUV) and near-UV (1771-2831 \AA, NUV) imaging to detect young massive stars and trace the recent star formation ...
Aller   +27 more
core   +2 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Dense Cores in IRDC G14.225-0.506 Revealed by ALMA Observations

open access: yesThe Astrophysical Journal
Dense cores in massive, parsec-scale molecular clumps are sites that harbor protocluster formation. We present results from observations toward a hub–filament structure of a massive infrared (IR) dark cloud G14.225-0.506 using the Atacama Large ...
Yanhanle Zhao   +4 more
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

JWST-FEAST: Feedback in Emerging extrAgalactic Star clusTers: Calibration of Star Formation Rates in the Mid-infrared with NGC 628

open access: yesThe Astrophysical Journal
New JWST near-infrared imaging of the nearby galaxy NGC 628 from the JWST Cycle 1 program Feedback in Emerging extrAgalactic Star clusTers (JWST-FEAST) is combined with archival JWST mid-infrared imaging to calibrate the 21 μ m emission as a star ...
Daniela Calzetti   +21 more
doaj   +1 more source

Star-forming complexes in the polar ring galaxy NGC660

open access: yesOpen Astronomy, 2017
Galaxies with polar rings consist of two subsystems, a disk and a ring, which rotate almost in orthogonal planes. In this paper, we analyze the parameters characterizing the composition of the interstellar medium and star formation in star-forming ...
Smirnova Ksenia I.   +2 more
doaj   +1 more source

Star Forming Regions in Cepheus

open access: yes, 2008
104 pages, 25 tables, 35 figures; A chapter in the "Handbook of Star Forming Regions, Vol 1: The Northern Sky," ed. Bo Reipurth; ASP Monograph Series. Full resolution version can be found at http://www.konkoly.hu/staff/kun/handbook_chapters/
Kun, M., Kiss, Z. T., Balog, Z.
openaire   +2 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

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