Results 111 to 120 of about 44,874 (266)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Zeeman effect in sulfur monoxide: A tool to probe magnetic fields in star forming regions. [PDF]

Astron Astrophys, 2017
Cazzoli G, Lattanzi V, Coriani S, Gauss J, Codella C, Ramos AA, Cernicharo J, Puzzarini C.   +7 more
europepmc   +1 more source

The Orion Star Forming Region

, 2018
Talk given at Walk the Line ...
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Investigating the Star-forming Sites in the Outer Galactic Arm

The Astronomical Journal
We aim to investigate the global star formation scenario in star-forming sites AFGL 5157, [FSR2007] 0807 (hereafter FSR0807), [HKS2019] E70 (hereafter E70), [KPS2012] MWSC 0620 (hereafter KPS0620), and IRAS 05331+3115 in the outer Galactic arm.
Aayushi Verma, Saurabh Sharma, Lokesh K. Dewangan, Devendra K. Ojha, Kshitiz Mallick, Ram Kesh Yadav, Harmeen Kaur, Tarak Chand, Mamta, Archana Gupta   +9 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Young Stellar Objects in the Massive Star-forming Regions W51 and W43. [PDF]

Astrophys J, 2017
Saral G, Hora JL, Audard M, Koenig XP, Martínez-Galarza JR, Motte F, Nguyen-Luong Q, Saygac AT, Smith HA.   +8 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Magnetic Field Alignment Relative to Multiple Tracers in the High-mass Star-forming Region RCW 36

The Astrophysical Journal
We use polarization data from SOFIA HAWC+ to investigate the interplay between magnetic fields and stellar feedback in altering gas dynamics within the high-mass star-forming region RCW 36, located in Vela C.
Akanksha Bij, Laura M. Fissel, Lars Bonne, Nicola Schneider, Marc Berthoud, Dennis Lee, Giles A. Novak, Sarah I. Sadavoy, Thushara G. S. Pillai, Maria Cunningham, Paul Jones, Robert Simon   +11 more
doaj   +1 more source

Structure of photodissociation fronts in star-forming regions revealed by observations of high-J CO emission lines with Herschel. [PDF]

Astron Astrophys, 2018
Joblin C, Bron E, Pinto C, Pilleri P, Le Petit F, Gerin M, Le Bourlot J, Fuente A, Berne O, Goicoechea JR, Habart E, Köhler M, Teyssier D, Nagy Z, Montillaud J, Vastel C, Cernicharo J, Röllig M, Ossenkopf-Okada V, Bergin EA.   +19 more
europepmc   +1 more source