Results 121 to 130 of about 705,440 (315)

13C ISOTOPIC FRACTIONATION OF HC3N IN STAR-FORMING REGIONS: LOW-MASS STAR-FORMING REGION L1527 AND HIGH-MASS STAR-FORMING REGION G28.28-0.36 [PDF]

open access: yes, 2016
We observed the J = 9–8 and 10–9 rotational lines of three 13C isotopologues of HC3N in L1527 and G28.28-0.36, with the 45 m radio telescope of the Nobeyama Radio Observatory, in order to constrain the main formation mechanisms of HC3N in each source ...
K. Taniguchi, M. Saito, H. Ozeki
semanticscholar   +1 more source

Monitoring Water Masers in Star-Forming Regions [PDF]

open access: yesAstrophysics and Space Science, 2005
9 pages, 1 table, 11 figures. Accepted for publ. in Ap&SpSci. Refereed contribution to "Dense Molecular Gas around Protostars and in Galactic Nuclei", European Workshop 2004 on Astronomical Molecules. Eds. Y. Hagiwara, W.A. Baan, H.J.
Riccardo Cesaroni   +6 more
openaire   +3 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Global and Local Infall in the ASHES Sample (GLASHES). I. Pilot Study in G337.541

open access: yesThe Astrophysical Journal
Recent high-angular-resolution observations indicate the need for core growth to form high-mass stars. To understand the gas dynamics at the core scale in the very early evolutionary stages before being severely affected by feedback, we have conducted ...
Kaho Morii   +6 more
doaj   +1 more source

Sulphur abundance determinations in star-forming regions - I. Ionization correction factor [PDF]

open access: yes, 2016
In the present work we used a grid of photoionization models combined with stellar population synthesis models to derive reliable Ionization Correction Factors (ICFs) for the sulphur in star-forming regions.
O. Dors   +4 more
semanticscholar   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Tracking Star-forming Cores as Mass Reservoirs in Clustered and Isolated Regions Using Numerical Passive Tracer Particles

open access: yesThe Astrophysical Journal
Understanding the physical properties of star-forming cores as mass reservoirs for protostars and the impact of turbulence is crucial in star formation studies.
Shingo Nozaki   +3 more
doaj   +1 more source

Phosphorus-bearing molecules in solar-type star-forming regions: first PO detection [PDF]

open access: yes, 2016
Based on observations carried out as part of the Large Program ASAI (project number 012-12) with the IRAM 30 m telescope. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain).
B. Lefloch   +12 more
semanticscholar   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

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