Results 131 to 140 of about 1,323 (153)
nArgBP2 together with GKAP and SHANK3 forms a dynamic layered structure. [PDF]
Front Cell NeurosciLee SE, Chang S.
europepmc +1 more source
Crosstalk between protein post-translational modifications and phase separation. [PDF]
Cell Commun SignalLiu Y, Feng W, Wang Y, Wu B.
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Stargazin modulates AMPA receptor antagonism
Neuropharmacology, 2008AMPA receptors mediate the majority of fast synaptic transmission and underlie several forms of synaptic plasticity. AMPARs also have an important role in several neuronal pathologies. Therefore, studying the structure and function of these receptors is important for understanding general mechanisms of synaptic transmission as well as for the ...
Valentin Stein, Barbara Cokic
openaire +3 more sources
Stargazin differentially modulates ampakine gating kinetics and pharmacology
Biochemical Pharmacology, 2018It was previously reported that Stargazin (STG) enhances the surface expression of AMPA receptors, controls receptor gating and slows channel desensitization as an auxiliary subunit of the receptors. Ampakines are a class of AMPA receptor positive allosteric modulators that modify rates of transmitter binding, channel activity and desensitization ...
Daniel P. Radin +4 more
openaire +3 more sources
Stargazin involvement with bipolar disorder and response to lithium treatment
Pharmacogenetics and Genomics, 2008Multiple reports have implicated chromosomal region 22q13.1 in both schizophrenia and bipolar disorder. The calcium channel gamma-2 subunit gene (cacng2, Stargazin) located on 22q13.1 was recently reported to be associated with schizophrenia. We aimed to examine the expression levels of Stargazin in post-mortem brain samples of patients with ...
Silberberg, G +9 more
openaire +4 more sources
Stargazin and the AMPA receptor
Science, 2016Structural Biology AMPA-subtype ionotropic glutamate receptors (AMPARs) mediate fast excitatory neurotransmission and contribute to higher cognitive processes such as learning and memory. In the brain, AMPARs exist as protein-protein complexes with various auxiliary subunits that tightly control AMPAR trafficking, gating, and pharmacology.
openaire +2 more sources
Learning from stargazin: the mouse, the phenotype and the unexpected
Current Opinion in Neurobiology, 2006The stargazin gene (also referred to as Cacng2) has been identified by forward genetics in a spontaneous mouse mutant with ataxic gait, upward head-elevating movements (hence the name stargazer for the mouse) and episodes of spike-wave discharges. Stargazin is related to the gamma-1 subunit of skeletal muscle voltage-dependent calcium channel (VDCC ...
Osten, P., Stern-Bach, Y.
openaire +4 more sources
Stargazin interacts functionally with the AMPA receptor glutamate-binding module
Neuropharmacology, 2007Neuronal AMPA receptors comprise pore forming glutamate receptor (GluR) proteins and auxiliary transmembrane AMPA receptor regulatory (TARP) subunits. TARPs traffic AMPA receptors to synapses and regulate channel gating. Both intracellular and extracellular regions in TARPs regulate AMPA receptors; however, the details for these interactions remain ...
Yuko Fukata +4 more
openaire +3 more sources