Results 231 to 240 of about 1,654,341 (292)

A Cooperative Release of Mitochondrial DNA From Platelets and Neutrophils Drives an Interferon Signature in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

STAT3 and STAT6 activation in lung tissues correlates with inflammatory and clinical traits in COPD. [PDF]

ERJ Open Res
Contoli M, Miglietta D, Casolari P, Schiavi E, Fragni D, Semenzato U, Baraldi F, Baraldo S, Papi A.   +8 more
europepmc   +1 more source

Measuring the Impact: Magnetic Resonance Imaging Response of Sacroiliac Joints to Tumor Necrosis Factor Inhibitors in Youth With Axial Disease

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes (PROs) in youth with axial juvenile spondyloarthritis (axJSpA) initiating tumor necrosis factor inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

Mechanism of microcirculation disturbance in diabetic nephropathy: A review. [PDF]

Medicine (Baltimore)
Tang W, Liu H, Li X, Deng S, Gao C.
europepmc   +1 more source

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

Arthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis, Sabrina Narvesen, Deeva Robles Kuriplach, Karen Huang, Teja Sundar, Elizabeth Bagley, Joanna Parkes, Xinyu Jia, Nandhana Sudhan, Alfredo Guzman, Kanneboyina Nagaraju, Melissa Morales   +11 more
wiley   +1 more source

Protective Effect of <i>Gastrodia elata</i> Polysaccharide GEP-2 Against Oxidative Stress in Intestinal Epithelial NCM460 Cells. [PDF]

Int J Mol Sci
Yao Y, Wen X, He X, Liao D, Li M, Fan J, Liang R, Huang X, Li N.   +8 more
europepmc   +1 more source

Blood Gas Interpretation Under Hypothermic Conditions: A Comparative Study of Alpha-Stat and pH-Stat in Neonatal Hypoxic-Ischemic Encephalopathy. [PDF]

Int J Pediatr
Gandhi V, Lodha A, Mohammad K, Lodha A, Scott J, Rabi Y.   +5 more
europepmc   +1 more source

Management of Pregnancy in Women with Inflammatory Bowel Disease: Positioning Janus Kinase Inhibitors Within Current Evidence. [PDF]

Curr Issues Mol Biol
Colacurci D, Pellegrino R, Lamart A, Staiano D, De Costanzo I, Izzo M, Imperio G, Landa F, Scamardella G, Di Lella E, Federico A, Sarno L, Gravina AG.   +12 more
europepmc   +1 more source

Blood gas and lactate analysis in nesting loggerhead (Caretta caretta) and green (Chelonia mydas) sea turtles from southeastern Florida, USA. [PDF]

PLoS One
Giebink FE, Perrault JR, Toonder M, Hirsch SE, Aoki DM, Harms CA, Innis CJ, Stacy NI.   +7 more
europepmc   +1 more source

Correction. [PDF]

J Appl Stat
europepmc   +1 more source