Results 191 to 200 of about 250,824 (344)

Reciprocal Activation Between PLK1 and Stat3 Contributes to Survival and Proliferation of Esophageal Cancer Cells

, 2011
Yu Zhang, Xiaoli Du, Chengji Wang, De‐Chen Lin, Xia Ruan, Yanbin Feng, Yanqiu Huo, Haiyong Peng, Jing–Lu Cui, Tongtong Zhang, Yong–Quan Wang, Hongbing Zhang, Qimin Zhan, Ming‐Rong Wang   +13 more
openalex   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

Brucella abortus infection exploits ZDHHC3-mediated STAT3 palmitoylation to regulate host responses and promote persistence. [PDF]

Vet Res
Liu X, Yu J, Chen Y, Liu H, Liu N, Peng Q.   +5 more
europepmc   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

RETRACTION: Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells. [PDF]

Mediators Inflamm
Inflammation MO.
europepmc   +1 more source

AhR and STAT3: A Dangerous Duo in Chemical Carcinogenesis [PDF]

Marco Minacori, Sara Fiorini, Monia Perugini, Annamaria Iannetta, Giorgia Meschiari, Silvia Chichiarelli, Fabio Altieri, Pier Giorgio Natali, Margherita Eufemi   +8 more
openalex   +1 more source

Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma [PDF]

, 2018
Atish Mohanty, Natalie Sandoval, An T. Phan, Thang Van Nguyen, Robert W. Chen, Elizabeth Budde, Matthew Mei, Leslie Popplewell, Lan V. Pham, Larry W. Kwak, Dennis D. Weisenburger, Steven T. Rosen, Wing C. Chan, Markus Müschen, Vu N. Ngo   +14 more
openalex   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation

Cell, 1995
Zilong Wen, Z. Zhong, J. Darnell
semanticscholar   +1 more source

JNK-Dependent Stat3 Phosphorylation Contributes to Akt Activation in Response to Arsenic Exposure [PDF]

, 2012
Jing Liu, B. Chen, Yi-Ming Lu, Youfei Guan, Fei Chen   +4 more
openalex   +1 more source