Results 181 to 190 of about 34,891 (226)

Phyllostachyos Caulis in Taeniam extract stimulates longitudinal bone growth via IGF-1 and JAK2/STAT5 signaling in rats. [PDF]

PLoS One
An Y, Lee HW, Jung YC, Woo HJ, Kim Y, Kim H, Jeong YJ, Abd Ei-Aty AM, Jeong JH.   +8 more
europepmc   +1 more source

Mitochondrial ROS drive foam cell formation via STAT5 signaling in atherosclerosis. [PDF]

Sci Adv
Boccuni L, Marka F, Salzmann M, Schirripa A, Ableitner E, Siller M, Brekalo M, Haider P, Stojkovic S, Neumayer C, Örd T, Kollmann K, Assinger A, Decker T, Köcher T, Fischer MB, Mußbacher M, Bergthaler A, Hengstenberg C, Podesser BK, Kaikkonen MU, Wojta J, Hohensinner PJ.   +22 more
europepmc   +1 more source

A CD25-chemokine receptor complex initiates noncanonical IL-2 signaling. [PDF]

J Biol Chem
Lee HS, Kim SHJ, Aceil J, Meecham A, Gingras A, Ley K, Spangler JB, Ginsberg MH.   +7 more
europepmc   +1 more source

The STAT Signaling Pathway in HIV-1 Infection: Roles and Dysregulation. [PDF]

Int J Mol Sci
Tolomeo M, Cascio A.
europepmc   +1 more source

Stat5 binding to chromatin

, 2004
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STAT5 and STAT5 Inhibitors in Hematological Malignancies

Anti-Cancer Agents in Medicinal Chemistry, 2020
The JAK-STAT pathway is an important physiologic regulator of different cellular functions including proliferation, apoptosis, differentiation, and immunological responses. Out of six different STAT proteins, STAT5 plays its main role in hematopoiesis and constitutive STAT5 activation seems to be a key event in the pathogenesis of several ...
Manlio Tolomeo, Maria Meli, Stefania Grimaudo   +2 more
openaire   +2 more sources

Constitutively Active STAT5 Constructs

2012
The transcription factor Signal Tranducer and Activator of Transcription 5 (STAT5) plays an important role in many biological processes. To study STAT5 biology, several different constructs have been designed that render STAT5 constitutively active.
Lynn M, Heltemes-Harris, Michael A, Farrar   +1 more
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2,4,4′‐trichlorobiphenyl increases STAT5 transcriptional activity

Molecular Carcinogenesis, 2001
AbstractThe promoting effects of polychlorinated biphenyls (PCBs) have been studied extensively in a variety of two‐stage carcinogenesis models. However, the molecular mechanisms responsible for the promotion effects of PCBs have not been elucidated.
G G, Oakley, A L, Roe, R A, Blouin, T P, Twaroski, T C, Ganguly, M, Vore, H J, Lehmler, L W, Robertson   +7 more
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STAT5 regulates glioma cell invasion by pathways dependent and independent of STAT5 DNA binding

Neuroscience Letters, 2011
STAT5 activation in primary glioma was analyzed using antibody directed against phosphorylated STAT5 (pSTAT5), in all samples robust pSTAT5 immunostaining was detected, predominantly in the nucleus. We then used immunofluorescence, transcription factor binding assays and western blotting to study EGF-modulated STAT5 activation in the human U87 glioma ...
Shouqiang, Cao, Chao, Wang, Qian, Zheng, Ying, Qiao, Ke, Xu, Tao, Jiang, Anhua, Wu   +6 more
openaire   +2 more sources