Results 201 to 210 of about 30,689 (278)

Solitary fibrous tumor of the posterior fossa: a rare and atypical case report. [PDF]

open access: yesInt J Surg Case Rep
Hermassi MA   +5 more
europepmc   +1 more source

A Selective Pro‐Oxidant Drives Redox Reprogramming to Induce Ferroptosis and Immune Remodeling in Glioblastoma

open access: yesSmart Medicine, Volume 5, Issue 5, October 2026.
Rosasina selectively targets glioblastoma by activating the NCOA4‐NOX5 redox pathway, inducing ferroptosis, and remodeling the tumor immune microenvironment through M1‐like macrophage polarization. These coordinated mechanisms suppress tumor growth and establish Rosasina as a promising therapeutic candidate for glioblastoma.
Shilpi Singh   +11 more
wiley   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

open access: yesClinical &Experimental Allergy, Volume 56, Issue 10, Page 1162-1176, October 2026.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese   +11 more
wiley   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

open access: yesThe FEBS Journal, Volume 293, Issue 20, Page 5996-6010, October 2026.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger   +3 more
wiley   +1 more source

The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL‐8‐Dependent VEGF Regulation: An In Vitro Study

open access: yesInternational Endodontic Journal, Volume 59, Issue 10, Page 2143-2163, October 2026.
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa   +5 more
wiley   +1 more source

Targeting STAT3 to Modulate the Effectiveness of Cardioprotective Conditioning Strategies Against Myocardial Ischemia–Reperfusion Injury in Subjects With Diabetic Cardiomyopathy

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 20, October 2026.
ABSTRACT Myocardial ischemia–reperfusion injury (MIRI) is a major cause of cardiovascular morbidity and mortality. Reperfusion, although essential for myocardial restoration, can paradoxically exacerbate injury through oxidative stress, calcium overload, mitochondrial permeability transition pore opening and inflammatory infiltration. The vulnerability
Chunyan Wang   +7 more
wiley   +1 more source

245 Herbal Nettle and STAT6

open access: yesJournal of Animal Science, 2018
K Davis, M Corley, L Rutto
openaire   +2 more sources

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