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Signaling mechanisms, interaction partners, and target genes of STAT6
Cytokine and Growth Factor Reviews, 2006 Like other members of the signal transducer and activator of transcription (STAT) family of proteins, STAT6 has a dual role as signaling molecule and transcription factor.
Jutta Horejs-Hoeck, Albert Duschl
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Photocontrol of STAT6 dimerization and translocation
Molecular BioSystems, 2010Abstract Phosphorylation of signal transducers and activators of transcription (STAT) proteins is a key step in activation of the JAK–STAT signal transduction cascade. Here we describe an approach to selectively analyze the impact of STAT6 phosphorylation on STATdimerization, DNA binding and nuclear import by accessing six types of ...
Lahiri, S. +3 more
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Brain Tumor Pathology, 2016
This report describes clinicopathological findings, including genetic data of STAT6, in a solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) of the central nervous system in an 83-year-old woman with a bulge in the left forehead. She noticed it about 5 months before, and it had grown rapidly for the past 1 month.
Keisuke, Ishizawa +7 more
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This report describes clinicopathological findings, including genetic data of STAT6, in a solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) of the central nervous system in an 83-year-old woman with a bulge in the left forehead. She noticed it about 5 months before, and it had grown rapidly for the past 1 month.
Keisuke, Ishizawa +7 more
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IFN-alpha activates Stat6 and leads to the formation of Stat2:Stat6 complexes in B cells.
Journal of immunology (Baltimore, Md. : 1950), 1999IFN-alpha consists of a family of highly homologous proteins, which exert pleiotropic effects on a wide variety of cell types. The biologic activities of IFN-alpha are mediated by its binding to a multicomponent receptor complex resulting in the activation of the Janus kinase-STAT signaling pathway.
S, Gupta, M, Jiang, A B, Pernis
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STAT6 is not expressed in Kaposi sarcoma
Annals of Diagnostic Pathology, 2021Georgia, Karpathiou +2 more
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Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery, 2011
To study the distribution and expression of STAT6 and to examine the suggested roles of STAT6 in the pathogenesis of eosinophil infiltration in nasal polyps and to evaluate the role of STAT6 in the pathogenesis of nasal polyps.All selected cases met the enrollment criteria.
Qingsong, Cao +4 more
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To study the distribution and expression of STAT6 and to examine the suggested roles of STAT6 in the pathogenesis of eosinophil infiltration in nasal polyps and to evaluate the role of STAT6 in the pathogenesis of nasal polyps.All selected cases met the enrollment criteria.
Qingsong, Cao +4 more
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STAT6 in PMBL: pathogenic or passenger?
Blood, 2009In this issue of Blood , Ritz and colleagues report that mutations in the transcription factor STAT6 are common events in PMBL. As the treatment of hematologic cancers evolves from nonspecific cytotoxic drugs to targeted rationally designed therapies, the necessity for identifying key ...
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STAT6 joins the gain-of-function club
Journal of Allergy and Clinical Immunology, 2023Karin, Chen +2 more
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The roles of STAT6 in regulating B cell fate, activation, and function
Immunology Letters, 2021Bingbing Zha, Luman Wang
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