Results 231 to 240 of about 30,689 (278)

Regulation of immune signal integration and memory by inflammation-induced chromosome conformation. [PDF]

open access: yesProc Natl Acad Sci U S A
Daniel B   +8 more
europepmc   +1 more source

Signaling mechanisms, interaction partners, and target genes of STAT6

open access: yesCytokine and Growth Factor Reviews, 2006
Like other members of the signal transducer and activator of transcription (STAT) family of proteins, STAT6 has a dual role as signaling molecule and transcription factor.
Jutta Horejs-Hoeck   +2 more
exaly   +2 more sources

The biology of Stat4 and Stat6 [PDF]

open access: yesOncogene, 2000
IL-4 and IL-12 are cytokines that are important regulators of the proliferation, differentiation and functional capacity of lymphocytes. STATs (signal transducers and activators of transcription) are transcription factors that provide a direct link between the cytokine receptors and cytokine induced gene transcription.
Michael J Grusby, Andrea L Wurster
exaly   +3 more sources
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STAT6 and phosphorylated STAT6 are differentially expressed in lymphomas

Pathology - Research and Practice, 2022
The STAT6 pathway is implicated in the pathogenesis of various lymphomas; however, its immunohistochemical expression has not been fully investigated. Thus, the aim of this study was to investigate the immunohistochemical expression of the two forms of STAT6, phosphorylated or not, in a series of systemic lymphomas.Immunohistochemical expression of two
Georgia, Karpathiou   +6 more
openaire   +2 more sources

Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II [PDF]

open access: yesEMBO Journal, 2002
STAT6 is a central mediator of IL-4-induced gene responses. STAT6-mediated transcription is depend ent on the C-terminal transcription activation domain (TAD), but the mechanisms by which STAT6 activates transcription are poorly understood. Here, we have identified the staphylococcal nuclease (SN)-like domain and tudor domain containing protein p100 as
Jie Yang, Marko Pesu, Olli Silvennoinen
exaly   +3 more sources

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