Cannabidiol-Dominant <i>Cannabis sativa</i> L. Inflorescence Extract Ameliorates Atopic Dermatitis by Modulating NLRP3 Inflammasome and JAK1/STAT6 Signaling in DNCB-Induced Mice. [PDF]
Han JY +8 more
europepmc +1 more source
Activating an interleukin 4-FLT3-STAT6 axis in multipotent progenitors restores lymphopoiesis in inflammation and aging. [PDF]
Yao J, Wang Y, Zhang Y.
europepmc +1 more source
Multi-level transcriptional control of specific macrophage responses. [PDF]
Drakaki A, Huisman JMA, Hoeksema MA.
europepmc +1 more source
Spinal solitary fibrous tumor metastatic to the fourth ventricle: illustrative case. [PDF]
Wang R +4 more
europepmc +1 more source
Regulation of immune signal integration and memory by inflammation-induced chromosome conformation. [PDF]
Daniel B +8 more
europepmc +1 more source
Signaling mechanisms, interaction partners, and target genes of STAT6
Like other members of the signal transducer and activator of transcription (STAT) family of proteins, STAT6 has a dual role as signaling molecule and transcription factor.
Jutta Horejs-Hoeck +2 more
exaly +2 more sources
The biology of Stat4 and Stat6 [PDF]
IL-4 and IL-12 are cytokines that are important regulators of the proliferation, differentiation and functional capacity of lymphocytes. STATs (signal transducers and activators of transcription) are transcription factors that provide a direct link between the cytokine receptors and cytokine induced gene transcription.
Michael J Grusby, Andrea L Wurster
exaly +3 more sources
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STAT6 and phosphorylated STAT6 are differentially expressed in lymphomas
Pathology - Research and Practice, 2022The STAT6 pathway is implicated in the pathogenesis of various lymphomas; however, its immunohistochemical expression has not been fully investigated. Thus, the aim of this study was to investigate the immunohistochemical expression of the two forms of STAT6, phosphorylated or not, in a series of systemic lymphomas.Immunohistochemical expression of two
Georgia, Karpathiou +6 more
openaire +2 more sources
Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II [PDF]
STAT6 is a central mediator of IL-4-induced gene responses. STAT6-mediated transcription is depend ent on the C-terminal transcription activation domain (TAD), but the mechanisms by which STAT6 activates transcription are poorly understood. Here, we have identified the staphylococcal nuclease (SN)-like domain and tudor domain containing protein p100 as
Jie Yang, Marko Pesu, Olli Silvennoinen
exaly +3 more sources

