Results 81 to 90 of about 4,107,771 (287)

Engineering a CRISPR-associated IscB system for developing miniature genome-editing tools in human cells and mouse embryos

open access: yesNature Communications
IscB, as the putative ancestor of Cas9, possesses a compact size, making it suitable for in vivo delivery. OgeuIscB is the first IscB protein known to function in eukaryotic cells but requires a complex TAM (NWRRNA).
Fei Zhang   +5 more
doaj   +1 more source

Plain Meaning, Precedent, and Metaphysics: Interpreting the “Point Source” Element of the Clean Water Act Offense [PDF]

open access: yes, 2015
This Article, the fourth in a series of five, examines the continuing struggles to define “point source” and “nonpoint source” under the Clean Water Act.
Miller, Jeffrey G.
core   +1 more source

The Water Isn’t Safe: The Dismal State of Texas Drinking Water Regulation [PDF]

open access: yes, 2018
This project won first place in the 2018 Signature Course Information Literacy Award. The award recognizes exemplary student work that achieves the learning outcomes of the Signature Course information literacy requirement, that students will be able to ...
Nguyen, Grace
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Optimizing root spatial distribution during the flower-boll stage can reduce yield losses from square stage drought in cotton

open access: yesBMC Plant Biology
Background Root spatial distribution, an important root function phenotype, is closely related to drought tolerance. Drought is known to hinder cotton development, but, the effects of drought at the square stage on the spatial distribution ...
Congcong Guo   +10 more
doaj   +1 more source

Distinct redox state regulation in the seedling performance of Norway maple and sycamore. [PDF]

open access: yesJ Plant Res, 2023
Alipour S   +3 more
europepmc   +1 more source

State regulation of the national currency exchange rate by gold and foreign currency reserve management [PDF]

open access: yes, 2018
Status of the national currency of Ukraine exchange rate has been characterized as unstable in recent years. Herewith, the Government has not implemented decisive measures on its stabilization, as a rule, underestimating the importance of the Hryvnia ...
Britchenko, Igor, Evhenii, Vlasenko
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Study on the motion characteristics of bedload sediment particles under different sediment transport intensities

open access: yesRiver
Bedload studies at the particle scale may help grasp the essence of the problem. Existing studies suffer from short filming durations, limited data volume, and a narrow range of sediment transport intensity variations.
Chunjing Liu   +6 more
doaj   +1 more source

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