Results 61 to 70 of about 1,232,717 (325)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

GENERALIZED TOPOLOGICAL TRANSITION MATRIX.

, 2016
. This article represents a major step in the unification of the theory of algebraic, topological and singular transition matrices by introducing a definition which is a generalization that encompasses all of the previous three.
de Rezende, Ketty A., R. Franzosa, K. A. De Rezende, Rezende, K. A. de, Vieira, Ewerton R., E. R. Vieira, Vieira, E. R., Franzosa, Robert, Franzosa, R.   +8 more
core   +1 more source

New Bounds for State Transition Matrices [PDF]

, 2022
International audienceWe address the problem of constructing matrix-valued interval observers for estimating state transition matrices for time-varying systems. We provide less conservative estimators than those in recent literature.
Malisoff, Michael, Mazenc, Frederic
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

State transition matrix and Markov-chain diagram for frequent volcanic eruptions: Krakatoa, Indonesia [PDF]

E3S Web of Conferences
Krakatoa has been a global attraction throughout history. Historical records of eruptions on this volcanic island complex provide thrill and excitement for visitors at once.
Harbowo Danni Gathot, Muliawati Triyana
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Pseudoentropy sum rule by analytical continuation of the superposition parameter

Journal of High Energy Physics
In this paper, we establish a sum rule that connects the pseudoentropy and entanglement entropy of the superposition state. Through analytical continuation of the superposition parameter, we demonstrate that the transition matrix and density matrix of ...
Wu-zhong Guo, Yao-zong Jiang, Jin Xu
doaj   +1 more source

A uniform definition of stochastic process calculi [PDF]

, 2012
We introduce a unifying framework to provide the semantics of process algebras, including their quantitative variants useful for modeling quantitative aspects of behaviors.
De Nicola, Rocco, Loreti, Michele, Massink, Mieke, Diego Lagella, Latella, Diego, Rocco De Nicola, Michele Loreti, De Nicola, R, Mieke Massink   +8 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Relative State Transition Matrix Using Geometric Approach for Onboard Implementation

Journal of Aerospace Technology and Management, 2017
In the present study relative state transition matrix was obtained. It matches the relative motion of 2 satellites while including the oblate perturbation. The used formulation applies the geometric approach and is in Cartesian frame.
Mankali P. Ramachandran
doaj