Results 81 to 90 of about 1,232,717 (325)

Generating Transition States of Isomerization Reactions with Deep Learning

, 2020
Lack of quality data and difficulty generating these data hinder quantitative understanding of reaction kinetics. Specifically, conventional methods to generate transition state structures are deficient in speed, accuracy, or scope.
William H., Green, John, Ingraham, Colin, Grambow, Lagnajit, Pattanaik   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Comparison of Analysis Methods for the Joint Connection-Level and Packet-Level Performance Evaluation of VoIP Traffic Networks

IEEE Access
In this paper, the performance of different mathematical models for the joint connection-level and packet-level numerical evaluation of systems with Voice over Internet Protocol (VoIP) traffic are studied and compared.
Mario A. Ramirez-Reyna, Felipe A. Cruz-Perez, Sandra Lirio Castellanos-Lopez, Genaro Hernandez-Valdez   +3 more
doaj   +1 more source

Study of the double Gamow-Teller transitions using the shell model approach

EPJ Web of Conferences, 2018
The double Gamow-Teller strength distributions in the lightest double beta-decay candidate 48Ca and its isotope 46Ca were calculated using the nuclear shell model by applying the single Gamow-Teller operator two times sequentially on the ground state of ...
Auerbach Naftali, Bui Minh-Loc
doaj   +1 more source

Sequence Recommendation with Fusion Transition Relation Regularization [PDF]

Jisuanji gongcheng
Sequential recommendation is a crucial task in recommendation systems for realizing personalized and dynamic recommendations by modeling users' sequential behaviors.
FENG Yali, WEN Wen, HAO Zhifeng, CAI Ruichu
doaj   +1 more source

TRANSITION MATRIX THEORY

, 2014
In this article we present a unification of the theory of algebraic, singular, topological and directional transition matrices by introducing the (generalized) transition matrix which encompasses each of the previous four.
Robert Franzosa, Ewerton R. Vieira
core  

Identifiability of Label Noise Transition Matrix

, 2022
The noise transition matrix plays a central role in the problem of learning with noisy labels. Among many other reasons, a large number of existing solutions rely on access to it.
Cheng, Hao, Zhang, Kun, Liu, Yang
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Low-complexity ATPM-VSIMM algorithm with adaptive model parameters

Tongxin xuebao, 2023
Aiming at the problem that for maneuvering target tracking, the accuracy of tracking degraded in interacting multiple model algorithms due to the fixed model sets and the fixed transition probability matrix, a low-complexity ATPM-VSIMM algorithm was ...
Hao ZENG, Wangqiang MU, Yang JIANG, Shunping YANG   +3 more
doaj   +2 more sources