Results 81 to 90 of about 1,066,098 (345)
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
An experimental investigation on three shear-critical reinforced concrete beams was performed to investigate the mechanism of shear fatigue. The first beam was simply tested to failure under monotonic loading to determine the static capacity, whereas the
Suryanto Benny +6 more
doaj +1 more source
Effects of moisture on torsion and flexure properties of graphite-epoxy composites [PDF]
The effects of moisture and temperature on unidirectional and multi-ply laminates of T300/934 and AS/3501 graphite-epoxy systems were investigated.
Adamson, M. J., Sumsion, H. T.
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The effect of temperature changes on to quasi-static tensile and flexural performance of glass fibre reinforced PA66 composites [PDF]
A significant method of reducing CO2 emissions in road vehicles is to reduce the vehicle mass. One means in which this can be achieved is to adopt lightweight materials such as thermoplastic composites.
Abhyankar, Hrushikesh +5 more
core
Flexural Performance of Alkali-Activated Slag Cements under Quasi-Static and Impact Loading
AbstractEffects of silicate modulus (Ms) of an activator solution and the matrix components of alkali-activated slag cement (AASC) on the flexural parameters of AASC mortars were investigated under static and low-velocity impact loadings. AASC mixtures in two different Ms (SiO2/Na2O) ratios were prepared by the partial replacement of ground granulated ...
Yardimci, Mert Yucel +2 more
openaire +4 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Feasibility study of fusion bonding for carbon fabric reinforced Polyphenylene Sulphide by hot-tool welding [PDF]
In recent years, there is a growing interest in joining techniques for thermoplastic composites as an alternative to adhesive bonding. In this article, a fusion bonding process called hot-tool welding is investigated for this purpose and the used ...
De Baere, Ives +2 more
core +1 more source

