Statin non-adherence: clinical consequences and proposed solutions [version 1; referees: 2 approved]
Large controlled clinical trials have demonstrated reductions with statin therapy in cardiovascular events in patients presenting with acute coronary syndromes and stable coronary heart disease and individuals at high risk of a cardiovascular event.
Robert S. Rosenson
doaj +1 more source
Statin-associated muscle symptoms (SAMS) in primary prevention for cardiovascular disease in older adults:A protocol for a systematic review and meta-analysis of randomised controlled trials [PDF]
IntroductionAlthough statins are commonly used for prevention of cardiovascular disease, there is limited evidence about statin-related adverse effects in older people. Statin-related adverse events (AEs), especially the statin-associated muscle symptoms
Albarqouni, Loai +4 more
core +1 more source
Risk of rheumatoid arthritis diagnosis in statin users in a large nationwide US study
Objective To evaluate the association between statin use and the risk of developing rheumatoid arthritis (RA) in a large, US case-control study. Methods Using the OptumLabs Data Warehouse, RA cases were identified as patients aged ≥18 years with ≥2 RA ...
Madeline N. Peterson +5 more
doaj +1 more source
Frequency Of Development Of Connective Tissue Disease In Statin-Users Versus Nonusers [PDF]
Statins have pleiotropic properties that may affect the development of connective tissue diseases (CTD). The objective of this study was to compare the risk of CTD diagnoses in statin users and nonusers. This study was a propensity score-matched analysis
Battafarano, Daniel F. +4 more
core +1 more source
There is limited data on high-intensity statin for secondary prevention in elderly acute myocardial infarction (AMI) patients above 75 years. This study aimed to assess the impact of high-intensity statin on 3-year outcomes in elderly AMI patients (> 75 ...
Ae-Young Her +7 more
doaj +1 more source
Statin use in resected, high-risk cutaneous melanoma: A multi-centre retrospective cohort study
Background: Pre-clinical and clinical studies propose that statins may have chemopreventive effects against cancer, suggesting their possible roles as adjunctive therapies for melanoma. Objective: To investigate the association between regular statin use
Charlie Yue Wang +6 more
doaj +1 more source
Statin therapy in critical illness : an international survey of intensive care physicians' opinions, attitudes and practice [PDF]
Background Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ failure.
Di Gangi, Stefania +6 more
core +1 more source
Statin Use Among Women and Men Following Coronary Artery Bypass Surgery
Background Limited data exist on sex differences in guideline‐recommended statin therapy for secondary prevention after coronary artery bypass surgery (CABG).
Sigrid Sandner +11 more
doaj +1 more source
Background Statins are guideline‐recommended medications that reduce cardiovascular events in patients with diabetes. Yet, statin use is concerningly low in this high‐risk population.
Ashish Sarraju +5 more
doaj +1 more source
Statins are related to impaired exercise capacity in males but not females. [PDF]
Exercise and statins reduce cardiovascular disease (CVD). Exercise capacity may be assessed using cardiopulmonary exercise testing (CPET). Whether statin medication is associated with CPET parameters is unclear.
Martin Bahls +8 more
doaj +1 more source

