Results 71 to 80 of about 26,575,973 (337)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Statistical Models for Company Growth [PDF]

SSRN Electronic Journal, 2003
Minor changes, submitted to Physica ...
Wyart, Matthieu, Bouchaud, Jean-Philippe
openaire   +6 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Statistics in the p-model

Chaos, Solitons & Fractals, 2006
The p-model is a mathematical construction largely applied in physics to construct intermittent distributions on a real interval and in general to study diadic branching processes (cascades). The model produces a hierarchy of Id distributions u((n)) with n = 0, 1, 2..., referred to as generations, that may be used to mimic natural irregular signals at ...
Materassi M., Wernik A., Yordanova E.
openaire   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Landslide Susceptibility Mapping Considering Landslide Spatial Aggregation Using the Dual-Frequency Ratio Method: A Case Study on the Middle Reaches of the Tarim River Basin

Remote Sensing
The phenomenon of landslide spatial aggregation is widespread in nature, which can affect the result of landslide susceptibility prediction (LSP). In order to eliminate the uncertainty caused by landslide spatial aggregation in an LSP study, researchers ...
Xuetao Yi, Yanjun Shang, Shichuan Liang, He Meng, Qingsen Meng, Peng Shao, Zhendong Cui   +6 more
doaj   +1 more source

Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio

BMC Medical Research Methodology, 2003
Background Cross-sectional studies with binary outcomes analyzed by logistic regression are frequent in the epidemiological literature. However, the odds ratio can importantly overestimate the prevalence ratio, the measure of choice in these studies ...
Hirakata Vânia N, Barros Aluísio JD
doaj   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Analysis of Bus Service Reliability Using A VL Data: Case Study of the City of Koper

Promet (Zagreb), 2008
This article uses a statistical approach to examine the bussystem reliability in the city of Koper. Four statistical modelswere developed using OLS to explain the effect of different variableson system reliability.
Dejan Paliska, Jurij Kolenc
doaj   +1 more source