Data interpretation and statistical significance
S M Balaji
doaj +1 more source
Clinical significance versus statistical significance: Does it matter in clinical practice? [PDF]
Mohanty CR +3 more
europepmc +1 more source
Statistical Significance Testing for Mixed Priors: A Combined Bayesian and Frequentist Analysis. [PDF]
Robnik J, Seljak U.
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Statistical significance and its critics: practicing damaging science, or damaging scientific practice? [PDF]
Mayo DG, Hand D.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The misunderstood P-value: why statistical significance is not enough in clinical practice. [PDF]
Ahmed ES, Butt MN.
europepmc +1 more source
There is life beyond the statistical significance. [PDF]
Ciapponi A +3 more
europepmc +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
ProOvErlap: Assessing feature proximity/overlap and testing statistical significance from genomic intervals. [PDF]
Gualandi N, Bertozzo A, Brancolini C.
europepmc +1 more source

