Results 161 to 170 of about 5,906,609 (291)

Shifting of Clinical Researches From Statistical Significance to Clinical Relevance. [PDF]

J Cosmet Dermatol
Pathania YS.
europepmc   +1 more source

One-Sided Multidimensional Statistical Significance Testing: A New Method of Calculating the Statistical Significance of Spectra Used to Demonstrate Magnetic Nanoparticle Sensitivity. [PDF]

J Phys D Appl Phys, 2022
Weaver JB, Weaver CV, Ness DB, Gordon-Wylie SW, Demidenko E.   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Conclusions reported in European Orthodontic Congress poster abstracts: are they based on clinical or statistical significance? [PDF]

Eur J Orthod
Yip DAX, Cobourne MT, Pandis N, Seehra J.   +3 more
europepmc   +1 more source

Evaluating statistical significance in a meta-analysis by using numerical integration. [PDF]

Comput Struct Biotechnol J, 2022
Lin YC, Liang YJ, Yang HC.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Common misinterpretations of statistical significance and <i>P</i>-values in dairy research. [PDF]

JDS Commun
Laven R, Yang DA.
europepmc   +1 more source

Variation across analysts in statistical significance, yet consistently small effect sizes. [PDF]

Proc Natl Acad Sci U S A, 2023
Mathur MB, Covington C, VanderWeele TJ.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Survival-inferred fragility of statistical significance in phase III oncology trials. [PDF]

NPJ Precis Oncol
Sherry AD, Liu Y, Msaouel P, Lin TA, Koong A, Lin C, Abi Jaoude J, Patel RR, Kouzy R, El-Alam MB, Miller AM, Owiwi M, Ofer J, Bomze D, McCaw ZR, Meirson T, Ludmir EB.   +16 more
europepmc   +1 more source