Results 71 to 80 of about 22,533,400 (291)
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
A Wavelet-Based Procedure for Steady-State Simulation Output Analysis
, 2003 The objective of this research is to develop an automated sequential procedure by which an asymptotically valid confidence interval is constructed for the steady-state mean of a simulation output process.
Lada, Emily Kate
core
Steady-state simulation scenarios, and computation methods for ASA.
, 2023 (a) Different scenarios requiring computation of the model steady state. Top: The pre-equilibration case, where the system is at steady state at the beginning of the experiment. This means that by t = t0 the system has reached its steady state (x*) under
Paul Stapor (8370540) +8 more
core +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
A Maximum Power Point Tracker with Automatic Step Size Tuning Scheme for Photovoltaic Systems
International Journal of Photoenergy, 2012 The purpose of this paper is to study on a novel maximum power point tracking (MPPT) method for photovoltaic (PV) systems. First, the simulation environment for PV systems is constructed by using PSIM software package.
Kuei-Hsiang Chao, Yu-Hsu Lee
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Transient exponential-Erlang queues and steady-state simulation [PDF]
Communications of the ACM, 1985 The transient probabilistic structure of M/E m /1 and E m /M/1 queues initialized in an arbitrary deterministic state is derived in discrete time. Computational algorithms for obtaining the required probabilities are provided, and their application in calculating a variety of system ...
openaire +1 more source