Results 221 to 230 of about 141,920 (316)

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen   +5 more
wiley   +1 more source

Head‐to‐Head Comparison of Four Ultrasound Elastography Techniques in Detecting Advanced Fibrosis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Elastography is an important noninvasive method for diagnosing advanced fibrosis (AF); however, evidence remains insufficient, particularly regarding acoustic radiation force impulse (ARFI) techniques. This prospective mulitcenter study concludes that vibration controlled transient elastography (VCTE) demonstrates superior diagnostic performance to ...
Jiahao Han   +8 more
wiley   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Stage-dependent dynamics of Apolipoprotein C3 across the spectrum of MASLD. [PDF]

open access: yesPLoS One
Messer EK   +8 more
europepmc   +1 more source

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