Results 231 to 240 of about 189,252 (309)

Comparable Diagnostic Accuracy but Discordant Thresholds Between FibroTouch and FibroScan: A Biopsy‐Based Comparative Study

Portal Hypertension &Cirrhosis, EarlyView.
In this biopsy‐controlled study, FibroTouch and FibroScan demonstrated comparable diagnostic accuracy for liver fibrosis staging (AUROCs > 0.900), but FibroTouch required consistently higher stiffness thresholds. These discrepancies were more pronounced in patients with MAFLD, highlighting the need for device‐specific cutoffs to avoid misclassification.
Min Wang, You Deng, Guanhua Zhang, Xinyan Zhao, Xiaoming Wang, Xiaojuan Ou, Min Li, Hong Ma, Yu Wang   +8 more
wiley   +1 more source

Controlled Attenuation Parameter and Gallstone Disease Risk: A Retrospective Cohort Study with Mediation Analysis and Longitudinal Trajectory Modeling, Emphasizing Gender-Specific Effects. [PDF]

Clin Epidemiol
Bai X, Li X, Wang Q, Yuan Q, Lu J, Gao M, Luo J, Yu W, Li H, Jiang G, He M, Jiang Y, Wang X, Chen Z, Yang H, Zhang C, Zhou D, Zhang L, Wang X.   +18 more
europepmc   +1 more source

Single‐nucleotide polymorphisms in coronary artery disease: Biological complexity, risk architecture, and implications for precision prevention

Precision Medical Sciences, EarlyView.
This graphical summary highlights the clinical application of single‐nucleotide polymorphisms‐based risk stratification in coronary artery disease. By integrating polygenic risk with clinical assessment, imaging, and preventive strategies, genetic information enables earlier risk identification, optimized screening, and personalized lifestyle and ...
Li Dai, Mosi Chen, Jun Hu, Lei Huang, Ye Yang, Chang Chen, Ying Zhuang, Yan Pan, Bingjun Qian   +8 more
wiley   +1 more source

Beta 2 adrenergic receptor agonists as a treatment for metabolic dysfunction-associated steatohepatitis (MASH). [PDF]

NPJ Metab Health Dis
Winkler BS, Stayer KM, Rao AK, Arif E, Mendenhall TT, Thomas KL, Driggers KR, Zuo X, Fitzgibbon W, Deng P, Su Y, Dang Y, Gerges M, Kagan D, Pasham V, Wolf B, Rockey DC, Hartman JH, Lipschutz JH.   +18 more
europepmc   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease. [PDF]

Nat Commun
Gao Y, Li C, Chang W, Du B, Ye X, Yeo YH, Xia Y, Guo H, Zhang X, Liu W, Bai R, Li B, Hong Y, Yao J, Lu L, Cao K, Yan K, Chen J, Li J, Hou Y, Zhang L, Shi Y.   +21 more
europepmc   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Niacin Derivatives in MASLD: Metabolic and Therapeutic Insights. [PDF]

Nutrients
Rojo-López MI, Niño-Narvión J, Antentas M, Fernández-Camins B, Martínez-Rojo E, Poca M, Martínez-Sánchez MA, Ramos-Molina B, Rossell J, Mauricio D, Julve J.   +10 more
europepmc   +1 more source

The relationship between acromegaly and hepatic steatosis: insights from FibroScan imaging. [PDF]

J Endocrinol Invest
Apaydin T, Kani HT, Keklikkiran C, Yilmaz Y, Yavuz DG.   +4 more
europepmc   +1 more source