Results 231 to 240 of about 141,920 (316)

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

Phytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

Pachymic Acid Alleviates Non-Alcoholic Fatty Liver Disease via FGF21-Mediated Inhibition of the p38 MAPK Pathway. [PDF]

Food Sci Nutr
Nie L, Ma D, Deng X, Erbu A, Wang F, Shi W, Li Z, Cui H, Wen W.   +8 more
europepmc   +1 more source

Bisphenols and Phthalates in Bottled Mineral Water: First Evidence of Co‐Occurrence, Estrogenic Activity, and Health Risk in Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), its structural analogs, and phthalates are synthetic chemicals widely used, with documented endocrine‐disrupting activity. This study aimed to develop and validate a selective multiresidue analytical method for the simultaneous determination of BPA, 10 bisphenol analogs, and six phthalates in PET‐bottled mineral water.
Giulia Boito Reyes, Lucas Correia Gonçalves, Fernanda Cristina Iba Molinari, José Eduardo Gonçalves   +3 more
wiley   +1 more source

miR-27a Suppresses Mitochondrial Function to Promote Hepatic Steatosis in High-Fat-Diet-Induced Obesity. [PDF]

Molecules
Yu Z, Yang X, Sun B, Jiang Y, Shi Y, Zhang M, Zhang S, Guan F.   +7 more
europepmc   +1 more source

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

VIEW, EarlyView.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin, Lijie Ma, Yuqing Yuan, Kaiyi Zhu, Zhaohui Tong, Qianmei Sun   +5 more
wiley   +1 more source

Hepatoprotective effects and mechanistic basis of cinnamaldehyde in preclinical liver disease models: A systematic review. [PDF]

J Int Med Res
Li J, Chen W, Lai Q, Zhao H.
europepmc   +1 more source

Readmissions After Surgery for Colorectal Liver Metastases: A Propensity Score Analysis From the Colorectal Liver Operative Metastasis International Collaborative (COLOMIC)

World Journal of Surgery, EarlyView.
The median survival in the readmission group was 39.7 months compared to 46.6 months in the control group, p = 0.43. ABSTRACT Background Readmission is considered as a surgical quality indicator. More data regarding predictors of readmission and outcomes after surgery for colorectal liver metastasis are needed.
Heidy Cos, Cristian D. Valenzuela, Omeed Moaven, Grey Leonard, John Stauffer, Nico R. Del Piccolo, Tan To Cheung, Carlos U. Corvera, Andrew Wisneski, Charles Cha, Kathleen Cummins, Greg Russell, Perry Shen   +12 more
wiley   +1 more source

Chronic intermittent hypoxia exacerbates hepatic steatosis in a microbiota-dependent manner in lean mice. [PDF]

mSystems
Zhang X, Zhong A, Liu Y, Zou J, Gu M, Zhu X, Xu H, Yin S.   +7 more
europepmc   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Discrimination of Steatotic and Non-Steatotic Chemicals Through Transcriptome Analysis in Primary Human Hepatocytes. [PDF]

Int J Mol Sci
Cramer von Clausbruch CA, Verheijen M, Callegaro G, Freedman JH, Ortega-Vallbona R, Palomino-Schätzlein M, Caiment F, Weiss C.   +7 more
europepmc   +1 more source