Results 91 to 100 of about 22,335 (252)

Metabolic Dysfunction-Associated Steatotic Liver Disease in Japan: Prevalence Trends and Clinical Background in the 10 Years before the Coronavirus Disease 2019 Pandemic

Medicina
Background and Objectives: The trends in metabolic dysfunction-associated steatotic liver disease (MASLD) and related metabolic dysfunctions in Japan are unknown.
Akira Sato, Yumiko Oomori, Rika Nakano, Tomokazu Matsuura   +3 more
doaj   +1 more source

Melatonin Promotes Improvement in Serum Lipid Levels and Liver Histopathology in Hyperlipidemic Rats

Lipids, EarlyView.
ABSTRACT Hyperlipidemia or dyslipidemia is the term used for the increase in lipid levels in blood plasma, usually occurring due to a high‐fat diet associated with a sedentary lifestyle. The increase in lipid levels can cause fatty infiltration in the liver known as hepatic steatosis, which can lead to inflammation, fibrosis, and necrosis consecutively.
Ana Cláudia Carvalho de Sousa, Jaiurte Gomes Martins da Silva, Érique Ricardo Alves, Laís Caroline da Silva Santos, Bruno José do Nascimento, Marcelle Mariana Sales de França, Vanessa Bischoff Medina, Ismaela Maria Ferreira de Melo, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley Teixeira   +9 more
wiley   +1 more source

Calcitriol Suppresses Platelet Activation and Thrombosis, Mitigating Cardiovascular Risks in Metabolic Dysfunction–Associated Steatotic Liver Disease

JACC: Basic to Translational Science
Summary: Metabolic dysfunction–associated steatotic liver disease is associated with vitamin D deficiency, and platelets exhibit hyperactivity. Zhang et al provide novel insights into the mechanisms underlying platelet hyperreactivity and thrombotic risk
Peng Zhang, MD, Huajie Xu, MD, Shujing Wu, MD, Wenxuan Zhou, MD, Luning Zhou, MD, Liping Han, PhD, Wei Zhang, PhD, Xiaoyu Lian, MD, Xin Zhao, MD, Haoxuan Zhong, MD, Bing Fan, MD, Hongyi Wu, MD, Zhiyong Qi, MD   +12 more
doaj   +1 more source

Circulating Omega‐3 Fatty Acids and Cardiometabolic Outcomes: A Systematic Review of Publications From UK Biobank

Lipids, EarlyView.
ABSTRACT Studies have shown that omega‐3 fatty acids may protect against cardiovascular diseases (CVDs) and related metabolic conditions. UK Biobank is a large cohort study that includes data on plasma omega‐3 fatty acids at study entry and health outcomes during the follow‐up period.
Warda Tul Firdous, Philip C. Calder
wiley   +1 more source

Prevalence of metabolic dysfunction-associated steatotic liver disease in inflammatory bowel disease patients: an Egyptian cross-sectional study

The Egyptian Journal of Internal Medicine
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized as a global health concern, with projections indicating it may become the leading cause of liver transplantation.
Shimaa Y. kamel, Mohamed Amin Sakr, Waleed Hamed, Hoda M. Farid, Amr Alaa El-Din, Ismail Anwar, Hany Shehab, Salma Omran, Mirella Sherif, Mohamed Negm, Nouran M. Bahig Elmihi, Dina Fathy   +11 more
doaj   +1 more source

Thy‐1 restricts steatosis and liver fibrosis in steatotic liver disease

Liver International
Abstract Background and Aims Steatotic liver disease (SLD) is generally considered to represent a hepatic manifestation of metabolic syndrome and includes a disease spectrum comprising isolated steatosis, metabolic dysfunction‐associated steatohepatitis, liver fibrosis and ultimately cirrhosis.
Valentin Blank, Thomas Karlas, Ulf Anderegg, Johannes Wiegand, Josi Arnold, Linnaeus Bundalian, Gabriela‐Diana Le Duc, Christiane Körner, Thomas Ebert, Anja Saalbach   +9 more
openaire   +4 more sources

Incomplete Spoiling Correction for 3D T1$$ {T}_1 $$ Mapping

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Assess the impact of incomplete spoiling and spatial saturation on T1$$ {T}_1 $$ mapping using the variable flip angle (VFA) spoiled gradient recalled echo sequence (SPGR). Develop a correction for incomplete spoiling that results in an accurate estimate of T1$$ {T}_1 $$, essential for quantitative MRI applications.
Gabriela Belsley, Damian J. Tyler, Matthew D. Robson, Elizabeth M. Tunnicliffe   +3 more
wiley   +1 more source

Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease

Nature Communications
The global rise in steatotic liver disease poses a significant public health challenge. While non-contrast computed tomography scans hold promise for opportunistic detection of steatotic liver disease, their potential for staging and risk assessment ...
Yuan Gao, Chunli Li, Wanxing Chang, Bai Du, Xianghua Ye, Yee Hui Yeo, Yingda Xia, Heng Guo, Xiaoming Zhang, Wei Liu, Ruobing Bai, Beibei Li, Yang Hong, Jiawen Yao, Le Lu, Kai Cao, Ke Yan, Jun Chen, Jie Li, Yang Hou, Ling Zhang, Yu Shi   +21 more
doaj   +1 more source

Endoscopic small bowel therapies for type 2 diabetes

Nutrition in Clinical Practice, EarlyView.
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel, Zehra Naseem, Prisha Gattu, Stephen Firkins, Roberto Simons‐Linares   +4 more
wiley   +1 more source

Early‐Life Dietary Protein Source Reshapes Gut Microbiota but Fails to Curtail Diet‐Induced Metabolic Syndrome in Young Rats

Obesity, EarlyView.
ABSTRACT Objective Dairy consumption plays a protective role in obesity that may be mediated through the gut microbiota. This study examined the role of dairy proteins, casein, whey, and complete dairy (skim milk powder), and a plant‐based alternative, soy, on gut microbiota composition, obesity susceptibility, and insulin sensitivity in early ...
Chunlong Mu, Micaela Hartslief, Jessica Chong, Shrushti Shah, Jennifer Thompson, Raylene A. Reimer, David C. Wright, Jane Shearer   +7 more
wiley   +1 more source