Results 81 to 90 of about 22,335 (252)

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Dynamic changes in the mouse hepatic lipidome following warm ischemia reperfusion injury

Scientific Reports
Liver failure secondary to metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most common cause for liver transplantation in many parts of the world.
Kim H. H. Liss, Muhammad Mousa, Shria Bucha, Andrew Lutkewitte, Jeremy Allegood, L. Ashley Cowart, Brian N. Finck   +6 more
doaj   +1 more source

Special Issue “Liver Fibrosis: Mechanisms, Targets, Assessment and Treatment”

Livers
Liver fibrosis is a significant challenge in hepatology, as it represents the common pathway of chronic liver injury due to various causes such as viral hepatitis, metabolic dysfunction-associated steatotic liver disease (MASLD), intoxication, alcohol ...
Ralf Weiskirchen, Tilman Sauerbruch
doaj   +1 more source

Estimated Body Fat Percentage and Triglyceride‐Glucose Index for Identifying MASLD in Lean Asian Adults: A Cross‐Sectional Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is increasingly prevalent among lean Asian populations, yet effective strategies for identifying high‐risk individuals remain limited. We investigated the associations of body fat percentage (BF%) and the triglyceride‐glucose (TyG) index with lean MASLD and evaluated their ...
Xiang‐Ran Kong, Ya‐Li Chen, Rui Li, Lu‐Xiang Shang, Sha Sha   +4 more
wiley   +1 more source

Impact of steatotic liver disease categories on atrial fibrillation in type 2 diabetes: a nationwide study

Scientific Reports
This study aims to investigate the incidence of new-onset atrial fibrillation (AF) in individuals with type 2 diabetes mellitus (T2DM) across different categories of steatotic liver disease (SLD). Using a health examination database between 2009 and 2012,
So Hyun Cho, Gyuri Kim, Kyu-na Lee, Rosa Oh, Ji Yoon Kim, Myunghwa Jang, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim   +10 more
doaj   +1 more source

Beyond the Heart: Hepatic Extracellular Volume Assessment in Patients With Cardiovascular Disease

Journal of Magnetic Resonance Imaging, EarlyView.
Kenichiro Suwa, Yuichiro Maekawa
wiley   +1 more source

Interactive Roles of Metabolic Dysfunction‐Associated Steatotic Liver Disease and Nutritional Status in the Prognosis of Patients With Hepatocellular Carcinoma After Surgical Resection

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prognostic effect of concurrent metabolic dysfunction‐associated steatotic liver disease (MASLD) on outcomes for hepatocellular carcinoma (HCC) patients remains unclear. The Prognostic Nutritional Index (PNI) reflects nutritional and inflammatory status and is a well‐known prognostic factor.
Chun‐Ting Ho, Chien‐An Liu, Chia‐Jung Ho, Yi‐Chen Lin, Shin‐Yu Tsai, Hao‐Jan Lei, Shu‐Cheng Chou, Yi‐Hsiang Huang, Ming‐Chih Hou, Jaw‐Ching Wu, Chien‐Wei Su   +10 more
wiley   +1 more source

Exploring the therapeutic potential of mitochondrial mechanism in metabolic dysfunction associated steatotic liver disease

Egyptian Liver Journal
Background Metabolic dysfunction-associated steatotic liver disease has emerged as the most prevalent liver disease with a rapidly increasing incidence worldwide. Targeting mitochondria in this condition opens up innovative avenues for the development of
Karthika Selvam, Shalinipriya Muthulakshmi Chinnaswamy, Sathish Jawahar, Venkatesh Gunasekaran   +3 more
doaj   +1 more source

Cardiometabolic Biomarkers for Disease Severity Prediction in Metabolic Dysfunction‐Associated Steatotic Liver Disease

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The impacts of cardiometabolic risk factors (CMRFs) and the biomarkers on disease severity in metabolic dysfunction‐associated steatotic liver disease (MASLD) remain elusive. Accordingly, a multicenter study by recruiting MASLD patients from a nationwide registry database was conducted with a total of 2882 MASLD patients (54.1% males, mean age 
Jee‐Fu Huang, Chi‐Yi Chen, Ming‐Jong Bair, Tzu‐Chun Lin, Ming‐Lun Yeh, Pei‐Chien Tsai, Yu‐Ju Wei, Chih‐Wen Wang, Po‐Chen Liang, Ming‐Yen Hsieh, Mei‐Hsuan Lee, Chia‐Yen Dai, Chung‐Feng Huang, Ming‐Lung Yu, Wan‐Long Chuang   +14 more
wiley   +1 more source

Impact of smoking and physical activity on cardiovascular outcomes in type 2 diabetes across steatotic liver disease categories

Scientific Reports
This study investigated the effect of smoking and regular physical activity (PA) on the composite risk of cardiovascular disease (CVD) in patients with type 2 diabetes mellitus (T2DM) across different steatotic liver disease (SLD) categories. We analyzed
So Hyun Cho, Gyuri Kim, Kyu-na Lee, Rosa Oh, Ji Yoon Kim, Myunghwa Jang, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim   +10 more
doaj   +1 more source