Results 61 to 70 of about 22,335 (252)

NAFLD becomes MASLD, frequency & characteristics of non obese metabolic dysfunction associated steatotic liver disease (MASLD) among patients seeking care at a tertiary medical facility

Journal of the Pakistan Medical Association
Objective: To determine the frequency and clinical characteristics of non-obese metabolic dysfunction-associated steatotic liver disease, distinguishing it from simple steatosis without metabolic dysfunction. Method: The cross-sectional, observational
Sumerah Jabeen, Fivzia Farooq Herekar, angbeen Aqeel, Manzoor Hussain   +3 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

The association between physical activity and metabolic dysfunction–associated steatotic liver disease: Evidence from the National Health and Nutrition Examination Survey and UK Biobank

Journal of International Medical Research
Objective There is limited prospective evidence on the association of physical activity with metabolic dysfunction–associated steatotic liver disease. We aimed to use data from two major databases to systematically quantify the correlation of physical ...
Yiping Shen, Meiyu Chen, Shiqi Zhu, Jiaxi Lin, Lihe Liu, Chengyi Zhu, Jinzhou Zhu, Chunfang Xu   +7 more
doaj   +1 more source

Non‐Nutritive Artificial Sweeteners Aspartame and Acesulfame‐K Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease in Male Ldlr−/− Mice

iNew Medicine, EarlyView.
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu, Xiaohua Jiang, Jianping Weng, Suowen Xu   +3 more
wiley   +1 more source

Shifting cell death modes in hepatic steatosis: from apoptosis to necroptosis

Endocrine Journal
In the liver, hepatocyte death occurs during the regeneration process following injury. While hepatocyte death triggers regeneration through hepatocyte proliferation in the non-steatotic liver, it impairs this process in the steatotic liver.
Yuka Inaba, Kohsuke Tsuchiya, Hiroshi Inoue   +2 more
doaj   +1 more source

Western Diet Combined With Chemical Induction: A Strategy for Rapid Development of MASLD Pathology in Mice

iNew Medicine, EarlyView.
ABSTRACT Objective The molecular mechanisms underlying the development of metabolic‐dysfunction‐associated steatotic liver disease (MASLD) are essential for developing appropriate treatments. The purpose of this study was to establish an MASLD model in mice with rapid and consistent progression.
Ting‐Ting Chen, Nan Li, Shuo Wang, Miao Sun, Rui Yang, Shi‐Hao Zhang, Xiao‐Lei Li, Chen Dong, Ke‐Yuan Chen, Wu‐Yi Sun, Na Zhou   +10 more
wiley   +1 more source

From Dysbiosis to Hepatic Inflammation: A Narrative Review on the Diet-Microbiota-Liver Axis in Steatotic Liver Disease

Microorganisms
The gut microbiota has emerged as a critical player in metabolic and liver health, with its influence extending to the pathogenesis and progression of steatotic liver diseases.
Andrea Pasta, Elena Formisano, Francesco Calabrese, Elisa Marabotto, Manuele Furnari, Giorgia Bodini, Maria Corina Plaz Torres, Livia Pisciotta, Edoardo Giovanni Giannini, Patrizia Zentilin   +9 more
doaj   +1 more source

Diagnostic Accuracy of Shear Wave Elastography for the Assessment of Congestive Liver Disease in Patients With Structural Heart Disease

Journal of Clinical Ultrasound, EarlyView.
Shear wave elastography demonstrated moderate diagnostic accuracy for detecting congestive liver disease in patients with structural heart disease. Increased liver stiffness was associated with echocardiographic markers of venous congestion, supporting the concept that elastography may serve as a noninvasive marker of cardiohepatic interaction ...
Edinéia Camargo Dziadzio, Maria Angelica Jungles Malikoski, Eduardo Henrique Bonotto, Sandra Monica Tochetto, Marco Stephan Lofrano‐Alves   +4 more
wiley   +1 more source

Global Co‐Occurrence Patterns of Ischemic Heart Disease and Metabolic Dysfunction–Associated Steatotic Liver Disease: Spatial Clusters, Risk Factors, and Quality‐of‐Care Index

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Ischemic heart disease and metabolic dysfunction–associated steatotic liver disease represent significant global health challenges, characterized by overlapping pathophysiological mechanisms.
Wei Wang, Wei‐dong Jiang, Lin Wang, Jin‐hui Sun, Zi‐jia Li, Ze‐zhong Wu, Ai‐qiong Qin, Shi Qiu, Wen Liu   +8 more
doaj   +1 more source

High‐Throughput Quantitative Chemical Shift‐Encoded MRI of the Liver

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Access to MRI is limited by lengthy exam times and inefficient utilization. Focused protocols can reduce exam times, but workflow variability and inefficient room turnaround contribute to conservative scheduling with long exam slots.
Garrett C. Fullerton, Jiayi Tang, Jitka Starekova, Julius F. Heidenreich, Ali Pirasteh, David T. Harris, Daiki Tamada, Collin J. Buelo, Dan W. Rettmann, Diego Hernando, Scott B. Reeder   +10 more
wiley   +1 more source