Results 131 to 140 of about 5,456,142 (288)

Calcitriol Suppresses Platelet Activation and Thrombosis, Mitigating Cardiovascular Risks in Metabolic Dysfunction–Associated Steatotic Liver Disease

JACC: Basic to Translational Science
Summary: Metabolic dysfunction–associated steatotic liver disease is associated with vitamin D deficiency, and platelets exhibit hyperactivity. Zhang et al provide novel insights into the mechanisms underlying platelet hyperreactivity and thrombotic risk
Peng Zhang, MD, Huajie Xu, MD, Shujing Wu, MD, Wenxuan Zhou, MD, Luning Zhou, MD, Liping Han, PhD, Wei Zhang, PhD, Xiaoyu Lian, MD, Xin Zhao, MD, Haoxuan Zhong, MD, Bing Fan, MD, Hongyi Wu, MD, Zhiyong Qi, MD   +12 more
doaj   +1 more source

Aisf practice guidance on pharmacological treatment of metabolic-dysfunction associated steatotic liver disease and steatohepatitis (masld/mash). A 2026 Update

Metabolic dysfunction–associated steatotic liver disease (MASLD) has rapidly emerged as the leading cause of chronic liver disease worldwide, gradually replacing viral hepatitis in clinical and epidemiological relevance. Italian data mirror global trends,
Antonio Gasbarrini, Elisabetta Bugianesi, Marco Carbone, Giacomo Germani, Francesco Tovoli, Giuseppe Marrone, Francesco Paolo Russo, Umberto Vespasiani-Gentilucci, Mauro Vigano, Simone Di Cola, Mario Masarone, Federico Ravaioli, Massimo Iavarone, Salvatore Petta, Fabio Marra, Giuseppe Cabibbo, Roberta D'Ambrosio, Stefano Gitto, Luca Miele, Francesca Romana Ponziani, Alessio Aghemo, Grazia Pennisi, Andrea Dalbeni, Angelo Armandi, Luca Valenti   +24 more
core   +1 more source

Steatotic liver disease and chronic viral hepatitis

Clinical & Experimental Hepatology
Steatotic liver disease (SLD) is a condition characterized by excessive fat accumulation within hepatocytes. In recent years, the nomenclature and diagnostic framework of the disease have evolved and the term SLD has replaced the previous fatty liver ...
Jakub Janczura, Alessandra Mangia, Krystyna Dobrowolska, Michał Brzdęk, Kinga Brzdęk, Małgorzata Wajdowicz, Iwona Gorczyca-Głowacka, Piotr M. Stępień, Dorota Zarębska-Michaluk   +8 more
doaj   +1 more source

Stage‐Dependent Prognostic Value of the Joint MASLD–NAFLD Fibrosis Score Phenotype Across the Cardiovascular–Kidney–Metabolic Syndrome Continuum: A Retrospective NHANES Cohort Analysis, 1999–2018

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The cardiovascular–kidney–metabolic (CKM) framework and metabolic dysfunction–associated steatotic liver disease (MASLD) describe a shared clinical continuum, but the prognostic value of joint fatty liver index (FLI)–NAFLD fibrosis score (NFS) phenotypes across CKM stages is uncertain.
Yi‐Fei Wang, Jian‐Li Zhang, Yun‐Fei Wang, Jun‐Peng Xiong, Rong‐Hui Yu, Ze‐Ping Hu   +5 more
wiley   +1 more source

Diagnostic Accuracy of Serum‐Based Fibrosis Scores for Clinically Significant Liver Fibrosis in an East Asian Cohort

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Serum‐based fibrosis scores are widely used for noninvasive risk stratification in chronic liver disease; however, direct comparisons across liver disease etiologies remain limited, particularly in Asian populations with a high prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection.
Sheng‐Feng Lin, Chun‐Chao Chang
wiley   +1 more source

Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease

Nature Communications
The global rise in steatotic liver disease poses a significant public health challenge. While non-contrast computed tomography scans hold promise for opportunistic detection of steatotic liver disease, their potential for staging and risk assessment ...
Yuan Gao, Chunli Li, Wanxing Chang, Bai Du, Xianghua Ye, Yee Hui Yeo, Yingda Xia, Heng Guo, Xiaoming Zhang, Wei Liu, Ruobing Bai, Beibei Li, Yang Hong, Jiawen Yao, Le Lu, Kai Cao, Ke Yan, Jun Chen, Jie Li, Yang Hou, Ling Zhang, Yu Shi   +21 more
doaj   +1 more source

Circulating Omega‐3 Fatty Acids and Cardiometabolic Outcomes: A Systematic Review of Publications From UK Biobank

Lipids, EarlyView.
ABSTRACT Studies have shown that omega‐3 fatty acids may protect against cardiovascular diseases (CVDs) and related metabolic conditions. UK Biobank is a large cohort study that includes data on plasma omega‐3 fatty acids at study entry and health outcomes during the follow‐up period.
Warda Tul Firdous, Philip C. Calder
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Incomplete Spoiling Correction for 3D T1$$ {T}_1 $$ Mapping

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Assess the impact of incomplete spoiling and spatial saturation on T1$$ {T}_1 $$ mapping using the variable flip angle (VFA) spoiled gradient recalled echo sequence (SPGR). Develop a correction for incomplete spoiling that results in an accurate estimate of T1$$ {T}_1 $$, essential for quantitative MRI applications.
Gabriela Belsley, Damian J. Tyler, Matthew D. Robson, Elizabeth M. Tunnicliffe   +3 more
wiley   +1 more source

Endoscopic small bowel therapies for type 2 diabetes

Nutrition in Clinical Practice, EarlyView.
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel, Zehra Naseem, Prisha Gattu, Stephen Firkins, Roberto Simons‐Linares   +4 more
wiley   +1 more source