Differential Mortality Risk by Age in Males and Females With Steatotic Liver Disease. [PDF]
Yan T +11 more
europepmc +1 more source
Hypercortisolism: An Under‐Recognised Pathway Linked to Multi‐System Complications
ABSTRACT The clinical understanding of hypercortisolism (HC) has evolved from a classic overt syndrome with florid Cushingoid features to a broader spectrum of disease that includes milder presentations, often referred to as mild autonomous cortisol secretion (MACS).
Hernan Daniel Sacoto, Vivian A. Fonseca
wiley +1 more source
Refining the Genetic Contribution to Type 2 Diabetes Subtypes
ABSTRACT Background Type 2 diabetes (T2D) is a complex and highly heterogeneous disease driven in part by genetic predisposition and can be stratified into clinical subgroups to aid disease management. We recently grouped T2D subjects in the Qatar Biobank (QBB) cohort into Severe Insulin‐Deficient Diabetes (SIDD), Severe Insulin‐Resistant Diabetes ...
Nayra M. Al‐Thani +5 more
wiley +1 more source
Metabolic dysfunction-associated steatotic liver disease and obstructive sleep apnea: A cohort analysis of prevalence and hepatic outcomes. [PDF]
Chowdhary R +11 more
europepmc +1 more source
The ‘Slow Burn’ Phenotype: How Relative Caloric Intake Reveals Hidden Cardiovascular Risk Beyond BMI
ABSTRACT Objective Body mass index (BMI) inadequately captures heterogeneity in cardiovascular (CV) risk. We hypothesised that a ‘Slow Burn’ phenotype, defined as lower‐than‐expected energy intake relative to BMI, age, and sex, identifies individuals at elevated CV risk across the BMI spectrum.
Yongin Cho +3 more
wiley +1 more source
The Chronic Hepatitis B and Metabolic Dysfunction-Associated Steatotic Liver Disease Paradox: Friend or Foe? [PDF]
Huang SC, Tseng TC.
europepmc +1 more source
ABSTRACT Aims To further characterise the effects of retatrutide on cardiometabolic risk, lipoprotein and inflammatory biomarkers were assessed post hoc in phase 2 trials of adults with obesity/overweight with or without type 2 diabetes (T2D). Materials and Methods Data were analysed from two randomised, double‐blind, placebo‐controlled phase 2 trials.
Giacomo Ruotolo +13 more
wiley +1 more source
Disparities in liver-related care among transgender adults with steatotic liver disease: a retrospective cohort study. [PDF]
Ortega Abad M +3 more
europepmc +1 more source
Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates
ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou +5 more
wiley +1 more source

