Results 61 to 70 of about 15,379,079 (345)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Push-out tests on demountable shear connectors of steel-concrete composite structures (LAC18.D) [PDF]

, 2018
peer reviewedThe deconstruction of steel-concrete composite structures in buildings and the later separation of the materials is a labour- and cost intensive work. The shear studs are welded on the steel beam and imbedded in the concrete deck and a large
ODENBREIT, Christoph, Veljkovic, Milan, Milan Veljkovic, Matthias Volker Braun, Odenbreit, Chirstoph, Martin Nijgh, Chirstoph Odenbreit, Braun, Matthias, KOZMA, Andras, BRAUN, Matthias Volker, Nijgh, Martin, Andras Kozma   +11 more
core   +1 more source

Experimental Analysis of the Post-Fracture Behaviour of Laminated Glass With Bolted Connections

Slovak Journal of Civil Engineering
Ensuring the sufficient residual resistance of glass structures after the failure of one glass ply to the failure of all the glass plies is an integral part of the design of glass structures.
Ondrušková Lucia, Brodniansky Ján, Brodniansky Ján, Klas Tomáš   +3 more
doaj   +1 more source

Numerical simulation and field measurement analysis of novel deep-sea aquaculture cage with spatial grid structure

Results in Engineering
Deep-sea aquaculture cages are important carriers for deep-sea resource development. This study proposes a novel hybrid framework that integrates spatial grid structures with H-shaped steel members, and features a vertically adjustable airbag system for ...
Qingmin Zhang, Wenfeng Du, Ming Xi, Liming Zhu, Zhonghang Hong   +4 more
doaj   +1 more source

Passive blast protection of buildings by ductile steel-based envelopes [PDF]

MATEC Web of Conferences
The growth of industrialization and the rapid expansion of densely populated urban areas have increased the risk caused by technological and man-made hazards.
Laszlo Robert, Ghicioi Emilian, Dinu Florea, Neagu Calin, Dubina Dan   +4 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Modeling Of Active Bending By The Method Newton-Raphson And The Modified Newton-Raphson

Civil and Environmental Engineering
The paper deals with the modelling and analysis of a single layer timber gridshell produced by active bending. Two geometrically nonlinear calculation methods, the Newton-Raphson method and the Modified Newton-Raphson method, are compared for the ...
Herda Roman, Slivanský Miloš, Sandanus Jaroslav   +2 more
doaj   +1 more source

Behaviour of Dissimilar Welded Connections of Mild Carbon (S235), Stainless (1.4404), and High-Strength (S690) Steels under Monotonic and Cyclic Loading

Metals
In the context of an increasing interest in the use of high-performance steels in the construction industry due to their superior mechanical properties, understanding the behaviour and assessing the performance of dissimilar welded connections becomes ...
Anna Ene, Aurel Stratan, Ioan Both
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source