Results 61 to 70 of about 867,403 (349)

Static Analysis of Selected Types of Roof Trusses Considering the Weakening of the Structural Elements

Slovak Journal of Civil Engineering
Failures of structural elements in historical roof trusses pose a significant challenge in the preservation and restoration of a cultural heritage. These trusses, traditionally constructed from wood, are exposed to various factors that contribute to ...
Martinkovičová Silvia, Sandanus Jaroslav, Brodniansky Ján, Ondrašinová Lucia   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Experimental Analysis of the Post-Fracture Behaviour of Laminated Glass With Bolted Connections

Slovak Journal of Civil Engineering
Ensuring the sufficient residual resistance of glass structures after the failure of one glass ply to the failure of all the glass plies is an integral part of the design of glass structures.
Ondrušková Lucia, Brodniansky Ján, Brodniansky Ján, Klas Tomáš   +3 more
doaj   +1 more source

Numerical simulation and field measurement analysis of novel deep-sea aquaculture cage with spatial grid structure

Results in Engineering
Deep-sea aquaculture cages are important carriers for deep-sea resource development. This study proposes a novel hybrid framework that integrates spatial grid structures with H-shaped steel members, and features a vertically adjustable airbag system for ...
Qingmin Zhang, Wenfeng Du, Ming Xi, Liming Zhu, Zhonghang Hong   +4 more
doaj   +1 more source

Passive blast protection of buildings by ductile steel-based envelopes [PDF]

MATEC Web of Conferences
The growth of industrialization and the rapid expansion of densely populated urban areas have increased the risk caused by technological and man-made hazards.
Laszlo Robert, Ghicioi Emilian, Dinu Florea, Neagu Calin, Dubina Dan   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Corrosion assessment on reinforced concrete and its service life prediction [PDF]

, 2005
Deterioration of structural concrete may be caused either by chemical or physical effects. Corrosion of embedded steel is a major cause of deterioration of concrete structures at the present time.
Syed Mohamad, Syed Burhanuddin Hilmi
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Modeling Of Active Bending By The Method Newton-Raphson And The Modified Newton-Raphson

Civil and Environmental Engineering
The paper deals with the modelling and analysis of a single layer timber gridshell produced by active bending. Two geometrically nonlinear calculation methods, the Newton-Raphson method and the Modified Newton-Raphson method, are compared for the ...
Herda Roman, Slivanský Miloš, Sandanus Jaroslav   +2 more
doaj   +1 more source

Behaviour of Dissimilar Welded Connections of Mild Carbon (S235), Stainless (1.4404), and High-Strength (S690) Steels under Monotonic and Cyclic Loading

Metals
In the context of an increasing interest in the use of high-performance steels in the construction industry due to their superior mechanical properties, understanding the behaviour and assessing the performance of dissimilar welded connections becomes ...
Anna Ene, Aurel Stratan, Ioan Both
doaj   +1 more source