Results 101 to 110 of about 64,475 (321)

Blue Supergiants in the Pinwheel Galaxy M101: Comparison with H II Region Chemical Abundances, Spectroscopic Distance, and an Independent Determination of the Hubble Constant

open access: yesThe Astrophysical Journal
We present a quantitative spectroscopic study of 13 blue supergiant stars in the Pinwheel Galaxy M101, based on data obtained with the Low Resolution Imaging Spectrometer available at the Keck I telescope.
Fabio Bresolin   +4 more
doaj   +1 more source

3D Hydrodynamical Simulations of Surface Convection in Red Giant Stars. Impact on spectral line formation and abundance analysis

open access: yes, 2007
We investigate the impact of 3D hydrodynamical model atmospheres of red giant stars at different metallicities on the formation of spectral lines of a number of ions and molecules.
Allende Prieto   +67 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Boron Abundances in Early B Dwarfs of the Galactic Open Cluster NGC 3293

open access: yesThe Astrophysical Journal
New boron abundances or upper limits have been determined for eight early B stars in the young Galactic open cluster NGC 3293, using UV spectra obtained by the Hubble Space Telescope Cosmic Origins Spectrograph.
Charles R. Proffitt   +6 more
doaj   +1 more source

A near field cosmology study of heavy elements in very metal-poor stars

open access: yes, 2012
Studying a range of old metal-poor stars provides information over cosmological timescales of our Galaxy. Such studies are indicative of the pristine gases and evolution of the Milky Way.
Hansen, Camilla. J.
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Stellar abundances and nucleosynthesis

open access: yes, 2016
Stellar abundances are essential parameters for many branches of astronomy. They are also particularly important as tests for theories of nucleosynthesis. Despite the encouraging results from band photometry, detailed spectroscopic analyses are still important in furthering knowledge of physical processes occurring in a variety of stellar objects. This
Ellis, R, Ellis, Richard S.
openaire   +1 more source

Cosmic abundances: The impact of stellar duplicity

open access: yes, 2004
The mass-transfer scenario links chemical peculiarities with stellar duplicity for an increasing number of stellar classes (classical and dwarf barium stars, subgiant and giant CH stars, S stars without technetium, yellow symbiotic stars, WIRRING stars ...
Jorissen, A., Van Eck, S.
core   +1 more source

The Gaia-ESO Survey: Homogenisation of stellar parameters and elemental abundances [PDF]

open access: diamond, 2023
A. Hourihane   +61 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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